PF-573228 is a potent and selective inhibitor of focal adhesion kinase (FAK) (IC₅₀ = 4 nM). PF-573,228 inhibits FAK phosphorylation on Tyr(397) with an IC₅₀ of 30-100 nM. Displays 50 - 250-fold selectivity for FAK over other protein kinases.
Item Number: BIOV2819-10
Unit of Measure: 10 MG
Manufacturer: BIOVISION
Manufacturer Number: 2819-10
Storage Temperature: Freezer (-20)
PF-573228 is a potent and selective inhibitor of focal adhesion kinase (FAK) (IC₅₀ = 4 nM). PF-573,228 inhibits FAK phosphorylation on Tyr(397) with an IC₅₀ of 30-100 nM. Displays 50 - 250-fold selectivity for FAK over other protein kinases.
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