IM-12 is a potent and selective GSK-3β inhibitor (IC₅₀ = 53 nM). It significantly increases β-catenin levels, leads to TCF-induction and promotes neuronal differentiation in human neural progenitor cells via activation of canonical Wnt signaling.
Item Number: BIOV2822-25
Unit of Measure: 25 MG
CAS Number: 1129669-05-1
Manufacturer: BIOVISION
Manufacturer Number: 2822-25
Chemical Formula: C22H20FN3O2
Storage Temperature: Freezer (-20)
IM-12 is a potent and selective GSK-3β inhibitor (IC₅₀ = 53 nM). It significantly increases β-catenin levels, leads to TCF-induction and promotes neuronal differentiation in human neural progenitor cells via activation of canonical Wnt signaling.
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