MK-4827 is a potent and selective PARP-1 and PARP-2 inhibitor with IC₅₀ values of 3.8 nM and 2.1 nM, respectively. It induces synthe tic lethality in preclinical tumour models with loss of BRCA and PTEN function.

Item Number: BIOV9462-5
Unit of Measure: 5 MG
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    Manufacturer: BIOVISION
    Manufacturer Number: 9462-5
    Storage Temperature: Freezer (-20)

    MK-4827 is a potent and selective PARP-1 and PARP-2 inhibitor with IC₅₀ values of 3.8 nM and 2.1 nM, respectively. It induces synthe tic lethality in preclinical tumour models with loss of BRCA and PTEN function.