UNC0379 is a selective, substrate-competitive inhibitor of the lysine methyltransferase SET8 (IC₅₀ = 7.3 µM; Kd = 18.3 µM). It is se lective for SET8 over 15 other methyltransferases, including G9a and GLP (IC₅₀s = >100 µM).
Item Number: BIOV9588-25
Unit of Measure: 25 MG
Manufacturer: BIOVISION
Manufacturer Number: 9588-25
Storage Temperature: Freezer (-20)
UNC0379 is a selective, substrate-competitive inhibitor of the lysine methyltransferase SET8 (IC₅₀ = 7.3 µM; Kd = 18.3 µM). It is se lective for SET8 over 15 other methyltransferases, including G9a and GLP (IC₅₀s = >100 µM).
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