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  3. PF-04418948 is a potent EP2 receptor antagonist with an IC₅₀ of 16 nM for human EP2 receptors. It also displays greater selectivity for EP2 receptors over EP1, 3, 4, DPI and CRTH2 receptors. It inhibits PGE2 induced increase in intracellular cAMP.

PF-04418948 is a potent EP2 receptor antagonist with an IC₅₀ of 16 nM for human EP2 receptors. It also displays greater selectivity for EP2 receptors over EP1, 3, 4, DPI and CRTH2 receptors. It inhibits PGE2 induced increase in intracellular cAMP.

Item Number: BIOVB1168-5
Unit of Measure: 5 MG
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    Manufacturer: BIOVISION
    Manufacturer Number: B1168-5
    Storage Temperature: Freezer (-20)

    PF-04418948 is a potent EP2 receptor antagonist with an IC₅₀ of 16 nM for human EP2 receptors. It also displays greater selectivity for EP2 receptors over EP1, 3, 4, DPI and CRTH2 receptors. It inhibits PGE2 induced increase in intracellular cAMP.