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The cysteine proteases termed lysosomal cathepsins have long been thoμght to be primarily involved in end-stage protein breakdown wi thin lysosomal compartments. Item Number: BIOV3741-100 Unit of Measure: 100 MCG Packaging: Vial 309.00 CHF 309.0 CHF Current delivery time on request	Wnt gene family members, including Wnt-1 throμgh Wnt-10, play a key role in regulating cellular growth and differentiation. Wnt-1 fu nctions as a key regulator of cellular adhesion. Item Number: BIOV3572R-100 Unit of Measure: 100 MCG Packaging: Vial 354.00 CHF 354.0 CHF Current delivery time on request	ROBO4 contains two fibronectin type-III domains and two Ig-like C2-type domains. ROBO4 is predominantly expressed in vascular endoth elium and is considered important for vascular development. ROBO4 is a receptor for Slit proteins Item Number: BIOV3625-100 Unit of Measure: 100 MCG Packaging: Vial 335.00 CHF 335.0 CHF Current delivery time on request	Lck is a membrane associated tyrosine protein kinases. The Lck gene has been shown to undergo rearrangement and overexpression in so me murine lymphomas. In human studies, it has been demonstrated that the Lck gene is localized to a site in Item Number: BIOV3498-100 Unit of Measure: 100 MCG Packaging: Vial 309.00 CHF 309.0 CHF Current delivery time on request
FOXL2 is a nuclear protein specially expressed in eyelids and in fetal and adult ovarian follicular cells. Defects in FOXL2 are caus e of blepharophimosis, ptosis and epicanthus inversus syndrome (BPES). It is an autosomal dominant disorder Item Number: BIOV3742-100 Unit of Measure: 100 MCG Packaging: Vial 309.00 CHF 309.0 CHF Current delivery time on request	Wnt gene family members, including Wnt-1 throμgh Wnt-10, play a key role in regulating cellular growth and differentiation. Wnt-1 is a cysteine-rich, secreted glycoprotein that associates with cell membranes and likely functions as a key re Item Number: BIOV3574R-100 Unit of Measure: 100 MCG Packaging: Vial 309.00 CHF 309.0 CHF Current delivery time on request	COCO, also known as DAND5, Dante, and CKTSF1B3, is a member of the DAN domain family of BMP antagonists that includes DAN (DAND1), G remlin/Drm (DAND2), PRDC (Protein Related to Dan and Cerberus; DAND3), and Cerberus (DAND4). Item Number: BIOV3626-100 Unit of Measure: 100 MCG Packaging: Vial 335.00 CHF 335.0 CHF Current delivery time on request	Lck is a membrane associated tyrosine protein kinases. The Lck gene has been shown to undergo rearrangement and overexpression in so me murine lymphomas. In human studies, it has been demonstrated that the Lck gene is localized to a site in Item Number: BIOV3499-100 Unit of Measure: 100 MCG Packaging: Vial 436.00 CHF 436.0 CHF Current delivery time on request
The initiation of gene transcription involves the ordered assembly of a multiprotein complex on proximal promoter elements such as t he TATA box. In addition to RNA polymerase II, the transcription factors class II (TFII) family of proteins Item Number: BIOV3743-100 Unit of Measure: 100 4G Packaging: Vial 436.00 CHF 436.0 CHF Current delivery time on request	SOYA-MAIZE OIL BLEND (FATTY ACIDS COMP.), UoM: 1 * 5,5 g Item Number: PROOBCR-162R Unit of Measure: 5,500 G Packaging: Amber ampoule 488.00 CHF 488.0 CHF Current delivery time on request	E6AP is an E3 ubiquitin ligase. Inheritance of a mutant maternal copy of this gene results in Angelman syndrome (AS) which is charac terized by severe mental retardation, seizures, ataxia, and EEG abnormalities. E6AP interacts with the type Item Number: BIOV3744-100 Unit of Measure: 100 4G Packaging: Vial 436.00 CHF 436.0 CHF Current delivery time on request	BCMA is a recently identified receptor for BAFF. It binds BAFF and April. BAFF and its receptors induce B cell development and survi val, activate NF-kB and c-Jun N-terminal kinase, and are involved in B cell associated autoimmune diseases. Item Number: BIOV3577-100 Unit of Measure: 100 MCG Packaging: Vial 335.00 CHF 335.0 CHF Current delivery time on request
The p53 tumor suppressor protein plays a major role in cellular response to DNA damage and other genomic aberrations. The activation of p53 can lead to either cell cycle arrest and DNA repair or apoptosis. p53 is phosphorylated at multiple Item Number: BIOV3515-100 Unit of Measure: 100 MCG Packaging: Vial 549.00 CHF 549.0 CHF Current delivery time on request	Histone acetyltransferases (HATs) have been implicated in a number of cellular functions including gene regulation, DNA synthesis, a nd repair. Item Number: BIOV3689-100 Unit of Measure: 100 MCG Packaging: Vial 309.00 CHF 309.0 CHF Current delivery time on request	BRD8 interacts with thyroid hormone receptor in a ligand-dependent manner and enhances thyroid hormone-dependent activation from thy roid response elements. BRD8 contains a bromodomain and is thoμght to be a nuclear receptor coactivator. Item Number: BIOV3506-100 Unit of Measure: 100 MCG Packaging: Vial 335.00 CHF 335.0 CHF Current delivery time on request	The tenascin family of extracellular matrix proteins includes Tenascin-C (also designated cytotactin or Tenascin), Tenascin-R (also designated restrictin, TN-R or janusin) and Tenascin-X. Tenascin proteins function as substrate-adhesion mol Item Number: BIOV3628-100 Unit of Measure: 100 MCG Packaging: Vial 347.00 CHF 347.0 CHF Current delivery time on request
Sodium glucose co transporters (SGLTs) are located in the brush-border membrane, but transported out of the cell across the basolate ral membranes by a facilitated sμgar transporter (GLUT). Item Number: BIOV3690-100 Unit of Measure: 100 MCG Packaging: Vial 391.00 CHF 391.0 CHF Current delivery time on request	High molecular weight serine protease inhibitors (serpins) are large superfamily of proteins, which bind to and inactivate serine pr oteinases. In 1995 Sprecher et al. cloned 2 novel serpins, termed PI8 and PI9, from human placenta cDNA libr Item Number: BIOV3748-100 Unit of Measure: 100 MCG Packaging: Vial 309.00 CHF 309.0 CHF Current delivery time on request	Fibronectin is a glycoprotein synthesized in the liver for the circulating blood plasma form, and is synthesized by many mesenchymal cells, for the extracellular matrix form. It is composed of two similar, but not identical protein chains, Item Number: BIOV3630-100 Unit of Measure: 100 MCG Packaging: Vial 309.00 CHF 309.0 CHF Current delivery time on request	Selectins are a family of carbohydrate-binding proteins involved in mediating cellular interactions with leukocytes. E-Selectin (als o called ELMA-1, CD62E) expressed on endothelial cells. Item Number: BIOV3631-100 Unit of Measure: 100 MCG Packaging: Vial 391.00 CHF 391.0 CHF Current delivery time on request

VWR / Merck Chemicals