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VWR / Merck Chemicals
GDC-0032 is a potent, and selective inhibitor of Class I PI3-K α, δ, and γ isoforms, with 30-fold less inhibition of the PI3K β isof orm relative to the PI3K α isoform. This next generation PI3-K inhibitor displays increased anti-tumor activity again
Item Number:
BIOV9573-5
Unit of Measure:
5 MG
158.00
CHF
158.0
CHF
Current delivery time on request
Angle-rotor 6x250 ml cpl., UoM: 1 * 1 items
Item Number:
HETT4266
Unit of Measure:
1 ST
4,360.00
CHF
4360.0
CHF
Current delivery time on request
Saxagliptin is hydroxyadamantyl compound that acts as a potent, selective and reversible dipeptidyl peptidase-4 (DPP-4) inhibitor (I C₅₀ = 26 nM). An anti-diabetic agent.
Item Number:
BIOV9528-50
Unit of Measure:
50 MG
171.00
CHF
171.0
CHF
Current delivery time on request
Conduritol B epoxide (CBE) is an irreversible inhibitor of glucocerebrosidase, also known as acid β-glucosidase, glucosylceramidase, GBA, or GBA1 (IC₅₀ = 9 μM). Inhibition of this lysosomal glucosidase
Item Number:
BIOV9574-25
Unit of Measure:
25 MG
574.00
CHF
574.0
CHF
Current delivery time on request
LX-4211 is a potent dual sodium-glucose cotransporter (SGLT)1 and SGLT2 inhibitor and an anti-diabetic agent. Sotagliflozin signific antly improves glycemic control, without increasing the rate of hypoglycemia measurements, in diabetic mice maintaine
Item Number:
BIOV9623-5
Unit of Measure:
5 MG
209.00
CHF
209.0
CHF
Current delivery time on request
Cardanol diene, UoM: 1 * 500 µG, CAS: 51546-63-5
Item Number:
CAYM23153-500
Unit of Measure:
500 MCG
162.00
CHF
162.0
CHF
Current delivery time on request
Fosaprepitant is a prodrug of Aprepitant (Cat. No. 9531) that acts as a selective, high-affinity antagonist of human substance P/neu rokinin 1 (NK1) receptors. After biologically activated to Aprepitant, it acts as an antiemetic agent.
Item Number:
BIOV9529-10
Unit of Measure:
10 MG
146.00
CHF
146.0
CHF
Current delivery time on request
INCB-024360 is a potent and selective indoleamine 2,3-dioxygenase (IDO1) inhibitor ( IC₅₀ = 10 nM); displays high selectivity over o ther related enzymes such as IDO2 or tryptophan 2,3-dioxygenase (TDO). Exhibits potent in vitro and in vivo immunomod
Item Number:
BIOV9477-25
Unit of Measure:
25 MG
839.00
CHF
839.0
CHF
Current delivery time on request
AG-555, UoM: 1 * 25 mg, CAS: 133550-34-2
Item Number:
CAYM23247-25
Unit of Measure:
25 MG
360.00
CHF
360.0
CHF
Current delivery time on request
L-778,123, UoM: 1 * 5 mg, CAS: 253863-00-2
Item Number:
CAYM22940-5
Unit of Measure:
5 MG
177.00
CHF
177.0
CHF
Current delivery time on request
Aprepitant is an anti-emetic compound that acts as a selective antagonist of human NK1 receptor (Kis = 3 and 454.1 nM for hNK1 and h NK3, respectively; IC₅₀ = 0.09 nM for hNK1). Its prodrug is Fosaprepitant (Cat. No. 9529).
Item Number:
BIOV9531-10
Unit of Measure:
10 MG
120.00
CHF
120.0
CHF
Current delivery time on request
Reticulol, UoM: 1 * 1 mg, CAS: 26246-41-3
Item Number:
CAYM23148-1
Unit of Measure:
1 MG
266.00
CHF
266.0
CHF
Current delivery time on request
FIIN-2 is a potent, selective, irreversible, next-generation covalent FGFR inhibitor. FIIN-2 is the first inhibitor that can potentl y inhibit the proliferation of cells dependent upon the gatekeeper mutants of FGFR1 or FGFR2.
Item Number:
BIOV9577-25
Unit of Measure:
25 MG
675.00
CHF
675.0
CHF
Current delivery time on request
S-trityl-L-Cysteine, UoM: 1 * 5 g
Item Number:
CAYM23236-5
Unit of Measure:
5 G
141.00
CHF
141.0
CHF
Current delivery time on request
IRAK-1-4 Inhibitor I is an inhibitor of interleukin-1 receptor associated kinase (IRAK) with IC₅₀ values of 0.3 μM and 0.2 μM for IR AK-1 and IRAK-4, respectively. It displays IC₅₀ values >10 µM in a panel of 27 other kinases tested.
Item Number:
BIOV9578-25
Unit of Measure:
25 MG
625.00
CHF
625.0
CHF
Current delivery time on request
Tridocosahexaenoin, UoM: 1 * 250 mg, CAS: 11094-59-0
Item Number:
CAYM23152-250
Unit of Measure:
250 MG
619.00
CHF
619.0
CHF
Current delivery time on request
Enteropeptidase substrate is a useful fluorogenic substrate for determining the activity of the enzyme enteropeptidase/enterokinase. This enzyme recognizes a highly specific amino acid sequence ‘DDDDK’ and cleaves after the lysine residue releasing t
Item Number:
BIOV9627-5
Unit of Measure:
5 MG
335.00
CHF
335.0
CHF
Current delivery time on request
SUSPENSION FITTING INTO ROTOR 4282, UoM: 1 * 1 items
Item Number:
HETT4285-A
Unit of Measure:
1 ST
2,420.00
CHF
2420.0
CHF
Current delivery time on request
FITC-LE(OMe)HD(OMe)-FMK is a fluorescein isothiocyanate (FITC) conjugate of the cell- permeable caspase-9 inhibitor LE(OMe)HD(OMe)-F MK that acts as an in situ marker for detection of caspase-9 in living cells. FITC-LE(OMe)HD(OMe)-FMK is nontoxic, a
Item Number:
BIOV9534-100
Unit of Measure:
100 AS
360.00
CHF
360.0
CHF
Current delivery time on request
SBI-0206965 is a potent, selective and cell permeable autophagy kinase ULK1 inhibitor. It inhibits ULK1 kinase with IC₅₀ of 108 nM a nd the highly related kinase ULK2 with IC₅₀ of 711 nM. SBI-0206965 suppresses ULK1-mediated phosphorylation events in
Item Number:
BIOV9580-25
Unit of Measure:
25 MG
625.00
CHF
625.0
CHF
Current delivery time on request
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