A dual inhibitor of mutant B-RafV600E and VEGFR2 (EC50s = 0.14 and 0.19 µM, respectively, in cell-based assays) that also inhibits w ild-type B-Raf, PDGFR, CSF1R, RET, c-KIT, SRC, and STE20 (IC50s = 20-100 nM), UoM: 1 * 5 mg, CAS: 927880-90-8

Item Number: CAYM16991-5
Unit of Measure: 5 MG
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    CAS Number: 927880-90-8
    Manufacturer: CAYMAN
    Manufacturer Number: 16991-5
    Chemical Formula: C24H16F6N6O
    Storage Temperature: Freezer (-20)

    A dual inhibitor of mutant B-RafV600E and VEGFR2 (EC50s = 0.14 and 0.19 µM, respectively, in cell-based assays) that also inhibits w ild-type B-Raf, PDGFR, CSF1R, RET, c-KIT, SRC, and STE20 (IC50s = 20-100 nM), UoM: 1 * 5 mg, CAS: 927880-90-8