GN25 blocks Snail binding to p53 and induces p53 expression in cancer cells in a KRas dependent manner. Oncogenic KRas has been show n to inhibit p53 function by inducing Snail to bind and eliminate p53 through exocytosis.

Numéro d'article : BIOV9430-5
Unité de mesure : 5 MG
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    Fabricant : BIOVISION
    Numéro du fabricant : 9430-5
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    GN25 blocks Snail binding to p53 and induces p53 expression in cancer cells in a KRas dependent manner. Oncogenic KRas has been show n to inhibit p53 function by inducing Snail to bind and eliminate p53 through exocytosis.