UNC0379 is a selective, substrate-competitive inhibitor of the lysine methyltransferase SET8 (IC₅₀ = 7.3 µM; Kd = 18.3 µM). It is se lective for SET8 over 15 other methyltransferases, including G9a and GLP (IC₅₀s = >100 µM).

Numéro d'article : BIOV9588-25
Unité de mesure : 25 MG
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    Fabricant : BIOVISION
    Numéro du fabricant : 9588-25
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    UNC0379 is a selective, substrate-competitive inhibitor of the lysine methyltransferase SET8 (IC₅₀ = 7.3 µM; Kd = 18.3 µM). It is se lective for SET8 over 15 other methyltransferases, including G9a and GLP (IC₅₀s = >100 µM).