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The MBD family of proteins includes MeCP2, MBD1, MBD2, MBD3 and MBD4. MBD2 is highly similar to MBD3 but only MBD2 targets the MeCP1 complex to methylate DNA. MBD2 has two isoforms, MBD2a and MBD2b. MBD2a is a 414 amino acids protein Numéro d'article : BIOV3232-100 Unité de mesure : 100 MCG Emballage : Vial 309.00 CHF 309.0 CHF Aktuelle Lieferfrist auf Anfrage	Heme oxygenase-1 (HO-1) or HSP32 is the inducible isoform of heme oxygenase which catalyzes the NADPH, O2 and cytochrome P450 reduct ase dependent oxidation of heme to carbon monoxide, iron and biliverdin that is immediately reduced to bilir Numéro d'article : BIOV3391-100 Unité de mesure : 100 MCG Emballage : Vial 354.00 CHF 354.0 CHF Aktuelle Lieferfrist auf Anfrage	TCTN1 belongs to the Tectonic protein family that regulate Hedgehog (Hh) pathway. During neural tube development, TCTN1 is required for the formation of most ventral cell types and for full Hh pathway activation. Numéro d'article : BIOV3088-100 Unité de mesure : 100 MCG Emballage : Vial 309.00 CHF 309.0 CHF Aktuelle Lieferfrist auf Anfrage	Bcl-xL is a 30 kDa anti-apoptotic protein belonging to the Bcl-2 family. Bcl-xL prevents apoptosis throμgh two different mechanisms: by heterodimerization with an apoptotic protein to inhibit its apoptotic effect, and by its direct pore-for Numéro d'article : BIOV3312-100 Unité de mesure : 100 MCG Emballage : Vial 360.00 CHF 360.0 CHF Aktuelle Lieferfrist auf Anfrage
Heme oxygenase (HO) is a microsomal enzyme that oxidatively cleaves heme, a pro-oxidant, into carbon monoxide and biliverdin. Two he me oxygenase isozymes, termed HO-1 and HO-2, have been identified so far. Numéro d'article : BIOV3392-100 Unité de mesure : 100 MCG Emballage : Vial 354.00 CHF 354.0 CHF Aktuelle Lieferfrist auf Anfrage	KLF4 belongs to the erythroid Kruppel-like factor (EKLF) family that is involved in the differentiation of epithelial cells and may also function in skeletal and kidney development. Numéro d'article : BIOV3089-200 Unité de mesure : 200 MCG Emballage : Vial 309.00 CHF 309.0 CHF Aktuelle Lieferfrist auf Anfrage	Cell death signal are transduced by death domain (DD), death effector domain (DED), and caspase recruitment domain (CARD) containing molecules. A novel protein that interacts with DED of caspase-8 and -10 Numéro d'article : BIOV3313-100 Unité de mesure : 100 MCG Emballage : Vial 335.00 CHF 335.0 CHF Aktuelle Lieferfrist auf Anfrage	Heterodimers between TCF3 and tissue specific basic helix loop helix (bHLH) proteins play important roles in determining tissue spec ific cell fate during embryogenesis, like muscle or early B cell differentiation. Numéro d'article : BIOV3090-100 Unité de mesure : 100 MCG Emballage : Vial 309.00 CHF 309.0 CHF Aktuelle Lieferfrist auf Anfrage
PTP1B is the founding member of the protein tyrosine phosphatase (PTP) family, which was isolated and identified based on its enzyma tic activity and amino acid sequence. PTPs catalyze the hydrolysis of the phosphate monoesters specifically Numéro d'article : BIOV3171-100 Unité de mesure : 100 MCG Emballage : Vial 410.00 CHF 410.0 CHF Aktuelle Lieferfrist auf Anfrage	Erk-5 shares high homology in the amino-terminal kinase domain with Erk1/2. However, the long carboxy-terminal kinase domain makes E rk5 a unique MAP kinase. Erk5 is activated by a variety of extracellular signals. The direct upstream kinase Numéro d'article : BIOV3397-100 Unité de mesure : 100 MCG Emballage : Vial 335.00 CHF 335.0 CHF Aktuelle Lieferfrist auf Anfrage	NF-kB is silenced in the cytoplasm by an inhibitory protein, IkB. IkB proteins are phosphorylated by IkB kinase complex consisting o f at least three proteins, IKK1/α, IKK2/β, and IKK3/g. External stimuli such TNF-α or other cytokines result Numéro d'article : BIOV3315-100 Unité de mesure : 100 MCG Emballage : Vial 373.00 CHF 373.0 CHF Aktuelle Lieferfrist auf Anfrage	Fas (APO-1, CD95) is a 45 kDa cell surface protein that mediates apoptosis when cross-linked with agonistic anti-Fas antibodies or F as ligand (FasL). FasL is a tumor necrosis factor (TNF)-related type II membrane protein and is expressed in Numéro d'article : BIOV3330-100 Unité de mesure : 100 MCG Emballage : Vial 373.00 CHF 373.0 CHF Aktuelle Lieferfrist auf Anfrage
LIN28 is a highly conserved cytoplasmic RNAbinding protein. Lin28 has an N-terminal cold shock domain and two Cterminal (CCHC) zin c finger motif. It is expressed in embryonic stem cells and embryonic carcinoma cells. Numéro d'article : BIOV3091-200 Unité de mesure : 200 MCG Emballage : Vial 309.00 CHF 309.0 CHF Aktuelle Lieferfrist auf Anfrage	Survivin is a newly described apoptosis inhibitor that is expressed in many human cancers, but undetectable in terminally differenti ated adult tissues. It has been shown that recombinant expression of Survivin conteracts apoptosis of B lymp Numéro d'article : BIOV3161-100 Unité de mesure : 100 MCG Emballage : Vial 335.00 CHF 335.0 CHF Aktuelle Lieferfrist auf Anfrage	Etk is a member of the Bruton’s tyrosine kinase family. Etk is expressed in a variety of hematopoietic, epithelial and endothelial c ells. It participates in multiple signal transduction pathways. Phosphorylation of tyrosine 566 by Src kinas Numéro d'article : BIOV3398R-100 Unité de mesure : 100 MCG Emballage : Vial 309.00 CHF 309.0 CHF Aktuelle Lieferfrist auf Anfrage	Bmf (for Bcl-2-modifying factor) is a novel BH3-only protein recently identified in human and mouse. The BH3 domain in Bmf is requir ed for both binding to Bcl-2 proteins and for triggering apoptosis. In healthy cells, Numéro d'article : BIOV3334R-100 Unité de mesure : 100 MCG Emballage : Vial 309.00 CHF 309.0 CHF Aktuelle Lieferfrist auf Anfrage
Focal adhesion kinase was identified as a 125 kDa substrate for the intrinsic protein tyrosine kinase activity of Src encoded pp60. The deduced amino acid sequence of FAK p125 has shown it to be a cytoplasmic protein tyrosine kinase Numéro d'article : BIOV3399-100 Unité de mesure : 100 MCG Emballage : Vial 335.00 CHF 335.0 CHF Aktuelle Lieferfrist auf Anfrage	Endonuclease G (EndoG) is a mitochondrion-specific nuclease that specifically activated by apoptotic stimuli and translocates to the nucleus during apoptosis. In nucleus, EndoG induces nucleosomal fragmentation of DNA independent of caspase Numéro d'article : BIOV3336R-100 Unité de mesure : 100 MCG Emballage : Vial 309.00 CHF 309.0 CHF Aktuelle Lieferfrist auf Anfrage	NORDIHYDROGUAIARETIC ACID Numéro d'article : CAYM70300-500 Unité de mesure : 500 MG Emballage : Glass bottle for solids 65.70 CHF 65.7 CHF Aktuelle Lieferfrist auf Anfrage	ILP-2 (for IAP-like protein-2) is a novel member of in the IAP (Inhibitor of Apoptosis) protein family. ILP-2 has high homology to I LP-1, but is encoded by a distinct gene that is solely expressed in testis of tested normal human tissues. Numéro d'article : BIOV3337-100 Unité de mesure : 100 MCG Emballage : Vial 309.00 CHF 309.0 CHF Aktuelle Lieferfrist auf Anfrage

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