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Smac/DIABLO is a mitochondrial protein that is released along with cytochrome c during apoptosis and activates cytochrome c/Apaf-1/c aspase-9 pathway. Smac/DIABLO binds to IAPs (Inhibitor of Apoptosis Proteins) and neutralizes the inhibitor Numéro d'article : BIOV3298-100 Unité de mesure : 100 MCG Emballage : Vial 309.00 CHF 309.0 CHF Délai de livraison actuel sur demande	Signaling lymphocytic activation molecule (SLAM/CD150) is expressed at hematopoietic tissue, such as memory T-cells, as well as at i mmature thymocytes. It has high-affinity self-ligand ability Numéro d'article : BIOV3226-200 Unité de mesure : 200 MCG Emballage : Vial 335.00 CHF 335.0 CHF Délai de livraison actuel sur demande	CaMKII is a member of calcium/calmodulin-activated kinase, functioning in neural synaptic stimulation and T-cell receptor signaling. CaMKII has catalytic and regulatory domains. The binding of Ca++/calmodulin to its regulatory domain releas Numéro d'article : BIOV3383-100 Unité de mesure : 100 MCG Emballage : Vial 335.00 CHF 335.0 CHF Délai de livraison actuel sur demande	Cytochrome P450 is mainly found in liver, and can metabolize a wide range of compounds such as organic solvents, acetaminophen, dime thylnitrosoamine and aliphatic alcohol, which have certain toxicological effects in humans. Numéro d'article : BIOV3084R-100 Unité de mesure : 100 MCG Emballage : Vial 309.00 CHF 309.0 CHF Délai de livraison actuel sur demande
D4-GDI (GDP dissociation inhibitor) is a negative regulator of the ras-related Rho family of GTPases. Since the Rho GTPases promote cytoskeleytal and membrane changes associated with apoptotic cell death, the removal of the D4-GDI block thr Numéro d'article : BIOV3385-100 Unité de mesure : 100 MCG Emballage : Vial 335.00 CHF 335.0 CHF Délai de livraison actuel sur demande	Profilin is a protein which maintains and shapes cytoskeleton by binding to actin. Profilin 1 has function in breast cancer cell mot ility, radial migration and glial cell adhesion. Numéro d'article : BIOV3306-100 Unité de mesure : 100 MCG Emballage : Vial 309.00 CHF 309.0 CHF Délai de livraison actuel sur demande	Elk-1 is a transcription factor that binds the serum response element (SRE) and mediates gene activity in response to serum and grow th factors. Elk-1 is phosphorylated by MAP kinase pathways and appears to be a direct target of activated MA Numéro d'article : BIOV3387-100 Unité de mesure : 100 MCG Emballage : Vial 335.00 CHF 335.0 CHF Délai de livraison actuel sur demande	Short/branched chain acyl-CoA dehydrogenase(ACADSB) belongs to the acyl-CoA dehydrogenase family of enzymes that catalyze the dehydr ogenation of acyl-CoA derivatives in the metabolism of fatty acids or branch chained amino acids. Numéro d'article : BIOV3150-100 Unité de mesure : 100 MCG Emballage : Vial 309.00 CHF 309.0 CHF Délai de livraison actuel sur demande
NAIP (neuronal apoptosis inhibitor protein) is a member of the IAPs (inhibitor of apoptosis proteins) that function in cell death pa thways to inhibit apoptosis. NAIP was discovered based on its association with a neurodegenerative disorder. Numéro d'article : BIOV3228-100 Unité de mesure : 100 MCG Emballage : Vial 335.00 CHF 335.0 CHF Délai de livraison actuel sur demande	The extracellular signal-regulated kinase 1 and 2 (Erk1 and Erk2) are closely related mitogen activated protein (MAP) kinases that a re activated throμgh the extracellular stimulation by many growth factors, mitogens and differentiation prom Numéro d'article : BIOV3085R-100 Unité de mesure : 100 MCG Emballage : Vial 322.00 CHF 322.0 CHF Délai de livraison actuel sur demande	Heat shock proteins (HSPs) are ubiquitously expressed in all organisms. A major function of HSP90 and other HSPs is to act as molecu lar chaperones. HSP90 forms a complex with glucocorticoid receptor (GR), rendering the non ligand-bound rece Numéro d'article : BIOV3389-100 Unité de mesure : 100 MCG Emballage : Vial 354.00 CHF 354.0 CHF Délai de livraison actuel sur demande	Protein kinases are enzymes that transfer a phosphate group from a phosphate donor, generally the g phosphate of ATP, onto an accept or amino acid in a substrate protein. By this basic mechanism, protein kinases mediate most of the signal tr Numéro d'article : BIOV3152-100 Unité de mesure : 100 MCG Emballage : Vial 410.00 CHF 410.0 CHF Délai de livraison actuel sur demande
Protein arginine methylation is a form of post-translational modification that is catalyzed by protein arginine methyltransferases ( PRMTs). PRMT6 catalyzes the sequential transfer of a methyl group from S-adenosyl-L-methionine to the side Numéro d'article : BIOV3086-100 Unité de mesure : 100 MCG Emballage : Vial 309.00 CHF 309.0 CHF Délai de livraison actuel sur demande	GSAP, gamma-secretase activating protein interacts with gamma secretase which chops up the amyloid precursor protein to senile plaqu es in Alzheimer’s disease. GSAP was found to increase the production amyloid peptide. Immunohistochemistry t Numéro d'article : BIOV3308-100 Unité de mesure : 100 MCG Emballage : Vial 347.00 CHF 347.0 CHF Délai de livraison actuel sur demande	Hexokinases phosphorylate glucose to produce glucose-6-phosphate, thus committing glucose to the glycolytic pathway. Alternative spl icing of the gene for GCK results in three tissue-specific forms of glucokinase, one found in pancreatic isl Numéro d'article : BIOV3153-100 Unité de mesure : 100 MCG Emballage : Vial 410.00 CHF 410.0 CHF Délai de livraison actuel sur demande	Hexokinases phosphorylate glucose to produce glucose-6-phosphate, thus committing glucose to the glycolytic pathway. Alternative spl icing of the gene for GCK results in three tissue-specific forms of glucokinase, one found in pancreatic isl Numéro d'article : BIOV3154-100 Unité de mesure : 100 MCG Emballage : Vial 410.00 CHF 410.0 CHF Délai de livraison actuel sur demande
The GLB1 gene encodes beta-galactosidase-1 (EC 3.2.1.23), a lysosomal hydrolase that cleaves the terminal beta-galactose from gangli oside substrates and other glycoconjugates (Yoshida et al., 1991 [PubMed 1907800]). Numéro d'article : BIOV3231-100 Unité de mesure : 100 MCG Emballage : Vial 347.00 CHF 347.0 CHF Délai de livraison actuel sur demande	Caspase family of cysteine proteases has been shown to play a key role in apoptosis. Similar to other caspases, caspase-6 is also sy nthesized as an inactive pro-enzyme that is processed in cells undergoing apoptosis. Numéro d'article : BIOV3156-100 Unité de mesure : 100 MCG Emballage : Vial 429.00 CHF 429.0 CHF Délai de livraison actuel sur demande	The mammalian proto-oncogene Ras encodes 21 kDa proteins (p21Ras) which exists in either a physiologically quiescent GDP-binding sta te or a GTPbinding signal-emitting state. Interaction of p21Ras with GTPase activating protein (GAP) Numéro d'article : BIOV3311-100 Unité de mesure : 100 MCG Emballage : Vial 309.00 CHF 309.0 CHF Délai de livraison actuel sur demande	Short/branched chain acyl-CoA dehydrogenase(ACADSB) belongs to the acyl-CoA dehydrogenase family of enzymes catalyze the dehydrogena tion of acyl-CoA derivatives in the metabolism of fatty acids or branch chained amino acids. Numéro d'article : BIOV3157-100 Unité de mesure : 100 MCG Emballage : Vial 309.00 CHF 309.0 CHF Délai de livraison actuel sur demande

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