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PARD (partitioning-defective) proteins are important in asymmetric cell division and polarized growth. PARD3 plays a vital role in t he formation of epithelial tight junctions. The PARD6-PARD3 complex links GTP-bound Rho small GTPases Numéro d'article : BIOV3260-100 Unité de mesure : 100 MCG Emballage : Vial 309.00 CHF 309.0 CHF Aktuelle Lieferfrist auf Anfrage	Calpains are cytosolic, calcium-dependent, cysteine proteases that are ubiquitously expressed in mammalian and avian tissues. Type I calpain requires micromolar amounts of calcium, while type II calpain requires millimolar amounts of calciu Numéro d'article : BIOV3189-100 Unité de mesure : 100 MCG Emballage : Vial 309.00 CHF 309.0 CHF Aktuelle Lieferfrist auf Anfrage	InSolution GSK-3 Inhibitor XVI CHIR99021 Numéro d'article : 361571-5MG Unité de mesure : 5 MG Emballage : Glass bottle 607.00 CHF 607.0 CHF Aktuelle Lieferfrist auf Anfrage	Death Associated Protein 1 (DAP1) is a 15 kDa protein that functions as a positive mediator of cell death initiated by interferon-ga mma. The DAP1 protein is praline-rich and possesses one SH3 binding motif, as well as several consensus prot Numéro d'article : BIOV3261-100 Unité de mesure : 100 MCG Emballage : Vial 360.00 CHF 360.0 CHF Aktuelle Lieferfrist auf Anfrage
TCTN2 is a member of the Tectonic protein family. Tectonic proteins are transmembrane proteins that regulate the Hedgehog (Hh)-signa ling pathway. Defects in TCTN2 can lead to Meckel syndrome type 8. This disorder is characterized by a comb Numéro d'article : BIOV3262-100 Unité de mesure : 100 MCG Emballage : Vial 309.00 CHF 309.0 CHF Aktuelle Lieferfrist auf Anfrage	The protein encoded by this gene is a catalytic subunit of the AMP-activated protein kinase (AMPK). AMPK is a heterotrimer consistin g of an alpha catalytic subunit, and non-catalytic beta and gamma subunits. AMPK is an important energy-sens Numéro d'article : BIOV3117-100 Unité de mesure : 100 MCG Emballage : Vial 410.00 CHF 410.0 CHF Aktuelle Lieferfrist auf Anfrage	The caspase family of cysteine proteases play a key role in apoptosis. Caspase-3 is the most extensively studied apoptotic protein a mong caspase family members. Numéro d'article : BIOV3004-100 Unité de mesure : 100 MCG Emballage : Vial 391.00 CHF 391.0 CHF Aktuelle Lieferfrist auf Anfrage	Cathepsin D is a normal lysosomal protease that is expressed in all cells. It is an aspartyl protease with a pH optimum in the range of 3-5, and contains two N-linked oligosaccharides. Cathepsin D is synthesized as an inactive 52 kDa pro Numéro d'article : BIOV3191R-100 Unité de mesure : 100 MCG Emballage : Vial 322.00 CHF 322.0 CHF Aktuelle Lieferfrist auf Anfrage
Fodrin is a universally expressed membrane-associated cytoskeletal protein consisting of α- and β-subunits. The protein is important for maintaining normal membrane structure and supporting cell surface protein function. α-Fodrin is one of Numéro d'article : BIOV3266-100 Unité de mesure : 100 MCG Emballage : Vial 309.00 CHF 309.0 CHF Aktuelle Lieferfrist auf Anfrage	Cathepsin L is a normal lysosomal cysteine endoproteases that is expressed in all cells. The latent 39 kDa pro-Cathepsin L must be p rocessed by cleavage of the 96 amino acid pro-peptide, to generate the active two-chain form made up of 21 Numéro d'article : BIOV3192-100 Unité de mesure : 100 MCG Emballage : Vial 322.00 CHF 322.0 CHF Aktuelle Lieferfrist auf Anfrage	Wee1 is a nuclear tyrosine protein kinase. The protein plays a role in suppressing eukaryotes’ entry into mitosis by inactivating cd c2 kinase by inhibiting tyrosine phosphorylation. The predicted molecular weight of the kinase is 72 kDa. Numéro d'article : BIOV3120-100 Unité de mesure : 100 MCG Emballage : Vial 335.00 CHF 335.0 CHF Aktuelle Lieferfrist auf Anfrage	NIK (NF-kB-inducing kinase) is a member of the MAP kinase kinase kinase family that binds TRAF2 and stimulates NF-kB activity. NIK w as initially isolated from a human B cell cDNA library and contains 795 amino acids with an apparent molecul Numéro d'article : BIOV3193R-100 Unité de mesure : 100 MCG Emballage : Vial 322.00 CHF 322.0 CHF Aktuelle Lieferfrist auf Anfrage
FATP4 is a transmembrane protein that is involved in the uptake and metabolism of long chain fatty acids. FATP4 has acyl-CoA synth ase activity and contains an AMP-binding motif. FATP4 is linked to insulin resistance and metabolic disorde Numéro d'article : BIOV3268-100 Unité de mesure : 100 MCG Emballage : Vial 309.00 CHF 309.0 CHF Aktuelle Lieferfrist auf Anfrage	The transcription factor ATF-2 (also called CRE-BP1) is a member of the ATF/CREB family of leucine zipper proteins. ATF-2 forms homo dimers and heterodimers with c-Jun to initiate CRE-dependent transcription. Phosphorylation of ATF-2 at Thr6 Numéro d'article : BIOV3359-100 Unité de mesure : 100 MCG Emballage : Vial 410.00 CHF 410.0 CHF Aktuelle Lieferfrist auf Anfrage	Bad is a member of the Bcl-2 family protein that selectively dimerize with Bcl-xL and Bcl-2 resulting in cell death. Survival factor s such as IL-3 can inhibit the apoptotic activity of Bad by activating intracellular signaling pathways that Numéro d'article : BIOV3269-100 Unité de mesure : 100 MCG Emballage : Vial 410.00 CHF 410.0 CHF Aktuelle Lieferfrist auf Anfrage	Transcription factor CREB binds the cAMP response element (CRE) and activates transcription in response to a variety of extracellula r signals including neurotransmitters, hormones, membrane depolarization, and growth or neurotrophic factors Numéro d'article : BIOV3360R-100 Unité de mesure : 100 MCG Emballage : Vial 309.00 CHF 309.0 CHF Aktuelle Lieferfrist auf Anfrage
Histone-lysine N- methyltransferase SETD3 has a function as methylation of Lys36 of histone H3 which represents a specific tag for e pigenetic transcriptional activation. It is highly expressed in muscular tissues. Numéro d'article : BIOV3197-200 Unité de mesure : 200 MCG Emballage : Vial 347.00 CHF 347.0 CHF Aktuelle Lieferfrist auf Anfrage	Hexokinases phosphorylate glucose to produce glucose-6-phosphate, thus committing glucose to the glycolytic pathway. This gene encod es hexokinase 3. Similar to hexokinases 1 and 2, this allosteric enzyme is inhibited by its product glucose- Numéro d'article : BIOV3198-100 Unité de mesure : 100 MCG Emballage : Vial 360.00 CHF 360.0 CHF Aktuelle Lieferfrist auf Anfrage	Tumor Necrosis Factor-alpha (TNF-α) is a potent lymphoid factor that exerts cytotoxic effects on a wide range of tumor cells and cer tain other target cells. Rat TNF-α is a 17 kDa protein containing 157 amino acid residues. Numéro d'article : BIOV3054-100 Unité de mesure : 100 MCG Emballage : Vial 309.00 CHF 309.0 CHF Aktuelle Lieferfrist auf Anfrage	Lamins are nuclear membrane structural components that are important in maintaining normal cell functions such as cell cycle control , DNA replication and chromatin organization. Numéro d'article : BIOV3267-100 Unité de mesure : 100 MCG Emballage : Vial 309.00 CHF 309.0 CHF Aktuelle Lieferfrist auf Anfrage

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