FTI-277 is a potent and selective farnesyltransferase (FTase) inhibitor (IC50 = 0.5 nM). It potently inhibits (IC₅₀ = 100 nM) H-Ras, but not the geranylgeranylated Rap1A processing in whole cells. FTI-277 blocks constitutive activation of mitogen-ac
Numero articolo: BIOV2874-5
Unità di misura: 5 MG
Numero CAS: 180977-34-8
Produttore: BIOVISION
Numero del produttore: 2874-5
Formula chimica: C22H29N3O3S2.HCl
Temperatura di stoccaggio: Freezer (-20)
FTI-277 is a potent and selective farnesyltransferase (FTase) inhibitor (IC50 = 0.5 nM). It potently inhibits (IC₅₀ = 100 nM) H-Ras, but not the geranylgeranylated Rap1A processing in whole cells. FTI-277 blocks constitutive activation of mitogen-ac
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