LY-2157299 is a potent and selective TGFβ receptor I (TβRI) inhibitor (IC₅₀ = 56 nM). LY-2157299 abolishes the TGFβ induced Smad2 ph osphorylation in HUVEC cells. It also shows dose dependent potentiation of VEGF or bFGF induced cell proliferation in
Numero articolo: BIOV9475-5
Unità di misura: 5 MG
Numero CAS: 700874-72-2
Produttore: BIOVISION
Numero del produttore: 9475-5
Formula chimica: C22H19N5O
Temperatura di stoccaggio: Freezer (-20)
LY-2157299 is a potent and selective TGFβ receptor I (TβRI) inhibitor (IC₅₀ = 56 nM). LY-2157299 abolishes the TGFβ induced Smad2 ph osphorylation in HUVEC cells. It also shows dose dependent potentiation of VEGF or bFGF induced cell proliferation in
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