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LIN28 is a highly conserved cytoplasmic RNAbinding protein. Lin28 has an N-terminal cold shock domain and two Cterminal (CCHC) zin c finger motif. It is expressed in embryonic stem cells and embryonic carcinoma cells. Numero articolo: BIOV3091-200 Unità di misura: 200 MCG Imballaggio: Vial 309,00 CHF 309.0 CHF Tempo di consegna attuale su richiesta	Survivin is a newly described apoptosis inhibitor that is expressed in many human cancers, but undetectable in terminally differenti ated adult tissues. It has been shown that recombinant expression of Survivin conteracts apoptosis of B lymp Numero articolo: BIOV3161-100 Unità di misura: 100 MCG Imballaggio: Vial 335,00 CHF 335.0 CHF Tempo di consegna attuale su richiesta	Etk is a member of the Bruton’s tyrosine kinase family. Etk is expressed in a variety of hematopoietic, epithelial and endothelial c ells. It participates in multiple signal transduction pathways. Phosphorylation of tyrosine 566 by Src kinas Numero articolo: BIOV3398R-100 Unità di misura: 100 MCG Imballaggio: Vial 309,00 CHF 309.0 CHF Tempo di consegna attuale su richiesta	Bmf (for Bcl-2-modifying factor) is a novel BH3-only protein recently identified in human and mouse. The BH3 domain in Bmf is requir ed for both binding to Bcl-2 proteins and for triggering apoptosis. In healthy cells, Numero articolo: BIOV3334R-100 Unità di misura: 100 MCG Imballaggio: Vial 309,00 CHF 309.0 CHF Tempo di consegna attuale su richiesta
Focal adhesion kinase was identified as a 125 kDa substrate for the intrinsic protein tyrosine kinase activity of Src encoded pp60. The deduced amino acid sequence of FAK p125 has shown it to be a cytoplasmic protein tyrosine kinase Numero articolo: BIOV3399-100 Unità di misura: 100 MCG Imballaggio: Vial 335,00 CHF 335.0 CHF Tempo di consegna attuale su richiesta	Endonuclease G (EndoG) is a mitochondrion-specific nuclease that specifically activated by apoptotic stimuli and translocates to the nucleus during apoptosis. In nucleus, EndoG induces nucleosomal fragmentation of DNA independent of caspase Numero articolo: BIOV3336R-100 Unità di misura: 100 MCG Imballaggio: Vial 309,00 CHF 309.0 CHF Tempo di consegna attuale su richiesta	NORDIHYDROGUAIARETIC ACID Numero articolo: CAYM70300-500 Unità di misura: 500 MG Imballaggio: Glass bottle for solids 65,70 CHF 65.7 CHF Tempo di consegna attuale su richiesta	ILP-2 (for IAP-like protein-2) is a novel member of in the IAP (Inhibitor of Apoptosis) protein family. ILP-2 has high homology to I LP-1, but is encoded by a distinct gene that is solely expressed in testis of tested normal human tissues. Numero articolo: BIOV3337-100 Unità di misura: 100 MCG Imballaggio: Vial 309,00 CHF 309.0 CHF Tempo di consegna attuale su richiesta
Five ionomycin-inducible complementary cDNAs, designated PAR1, 2, 3, 4 and 5, have been isolated from the prostate cancer cell line AT-3. Nucleotide sequencing identified PAR1 as the rat homolog of monkeyP-1, PAR2 as the injury-inducible ge Numero articolo: BIOV3447-100 Unità di misura: 100 MCG Imballaggio: Vial 309,00 CHF 309.0 CHF Tempo di consegna attuale su richiesta	Livin is a novel member in the IAP (inhibitor of apoptosis) protein family. Livin contains a single baculoviral IAP repeat (BIR) dom ain and a RING finger domain and has two isoforms termed Livin-α and Livin-β. Transfection of Livin protecte Numero articolo: BIOV3338-100 Unità di misura: 100 MCG Imballaggio: Vial 335,00 CHF 335.0 CHF Tempo di consegna attuale su richiesta	MyD88 was identified as an adapter molecule in the IL-1 signaling pathway. MyD88 associates with and recruits IRAK to the IL-1 recep tor complex in response to IL-1 treatment. Dominant-negative form of MyD88 attenuates IL-1R-mediated NF-B a Numero articolo: BIOV3244R-100 Unità di misura: 100 MCG Imballaggio: Vial 309,00 CHF 309.0 CHF Tempo di consegna attuale su richiesta	Bcl-3, a proto-oncogene, is believed to be involved in certain human B cell leukemias. It encodes a protein that functions as an IkB -like molecule for native NFkB, but is specific for the p50 subunit of NFkB. Numero articolo: BIOV3407-100 Unità di misura: 100 MCG Imballaggio: Vial 354,00 CHF 354.0 CHF Tempo di consegna attuale su richiesta
BLK, a BH3-containing protein that interacts with Bcl-2 and Bcl-xL, is a potent death agonist. Numero articolo: BIOV3175-100 Unità di misura: 100 MCG Imballaggio: Vial 360,00 CHF 360.0 CHF Tempo di consegna attuale su richiesta	Paxillin is one of the key components of integrin signaling. Tyrosine phosphorylation of paxillin is required for integrin-mediated cytoskeletal reorganization. Paxillin is phosphorylated by another focal adhesion component, focal adhesion Numero articolo: BIOV3448-100 Unità di misura: 100 MCG Imballaggio: Vial 335,00 CHF 335.0 CHF Tempo di consegna attuale su richiesta	Bcl-6 encodes a protein of 706 amino acids with a predicted molecular weight of 79 kDa. The Bcl-6 protein has homology with zinc fin ger transcription factors. However, little is known about its functions. Numero articolo: BIOV3408-100 Unità di misura: 100 MCG Imballaggio: Vial 354,00 CHF 354.0 CHF Tempo di consegna attuale su richiesta	PDK1 (Phosphoinositide-dependent protein kinase 1) plays an important role in cell signaling pathways and is involved in regulation of a wide variety of processes, including cell proliferation, differentiation and apoptosis. Numero articolo: BIOV3449-100 Unità di misura: 100 MCG Imballaggio: Vial 322,00 CHF 322.0 CHF Tempo di consegna attuale su richiesta
p53DINP1 (p53-dependent damage-inducible nuclear protein 1) encodes two proteins termed p53DINP1-α (27 kDa) and p53DINP1-β (18 kDa). p53DINP1 may regulate p53-dependent apoptosis throμgh phosphorylation at Ser46 and induction of p53AIP1. p5 Numero articolo: BIOV3340-100 Unità di misura: 100 MCG Imballaggio: Vial 322,00 CHF 322.0 CHF Tempo di consegna attuale su richiesta	Caspase-9 is one of the most important caspases among the caspase family members. Upon induction of apoptosis, cytochrome c released from mitochondria associates with procaspase-9/Apaf-1. Numero articolo: BIOV3409-100 Unità di misura: 100 MCG Imballaggio: Vial 309,00 CHF 309.0 CHF Tempo di consegna attuale su richiesta	HADH (Hydroxyacyl-Coenzyme A dehydrogenase) is a mitochondrial protein that catalyzes the oxidation of a wide variety of fatty acids , alcohols, and steroids. 3-hydroxyacyl-CoA dehydrogenase type II (HADH2) is a member of the short-chain deh Numero articolo: BIOV3246-100 Unità di misura: 100 MCG Imballaggio: Vial 309,00 CHF 309.0 CHF Tempo di consegna attuale su richiesta	Members of Oct family of transcription factors specifically interact with Octamer motif ATGCAAAT, a regulatory element important for tissue- and cell-specific transcription as well as for transcription of a number of housekeeping genes. All Numero articolo: BIOV3342-100 Unità di misura: 100 MCG Imballaggio: Vial 309,00 CHF 309.0 CHF Tempo di consegna attuale su richiesta

VWR / Merck Prodotti chimici