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MTA1 (metastasis-associated protein 1) is a component of the NURD (nucleosome remodeling and histone deacetylation) complex, which i s associated with ATP-dependent chromatin-remodeling and histone deacetylase activity. MTA1 functions in con Numero articolo: BIOV3799-100 Unità di misura: 100 4G Imballaggio: Vial 436,00 CHF 436.0 CHF Aktuelle Lieferfrist auf Anfrage	Vasodilator-stimulated phosphoprotein (VASP) belongs to the Ena/VASP family of adaptor proteins linking the cytoskeletal system to t he signal transduction pathways. VASP functions in cytoskeletal organization, fibroblast migration, platelet Numero articolo: BIOV3719-100 Unità di misura: 100 MCG Imballaggio: Vial 410,00 CHF 410.0 CHF Aktuelle Lieferfrist auf Anfrage	Xenopus Dickkopf (Dkk)-1 was initially discovered as a Wnt antagonist that plays an important role in head formation. By far, four m embers of Dkk have been identified in mammals. Each Dkk molecule contains two conserved cysteine-rich domain Numero articolo: BIOV3802A-100 Unità di misura: 100 MCG Imballaggio: Vial 309,00 CHF 309.0 CHF Aktuelle Lieferfrist auf Anfrage	Beclin is a Bcl-2 binding protein. Its structure includes a Bcl-2 binding coiled-coil region, and a leucine-rich nuclear export sign al (NES). Beclin protein colocalizes with intracytoplasmic organelles and nuclei in normal COS7 and MCF7 cel Numero articolo: BIOV3663-100 Unità di misura: 100 MCG Imballaggio: Vial 309,00 CHF 309.0 CHF Aktuelle Lieferfrist auf Anfrage
The human KLK gene family encodes about 15 serine proteases and has the potential to serve as cancer biomarkers. The Kallikrein 12 ( KLK 12) is one the KLK members located on chromosome 19. Numero articolo: BIOV3720-100 Unità di misura: 100 MCG Imballaggio: Vial 309,00 CHF 309.0 CHF Aktuelle Lieferfrist auf Anfrage	Xenopus Dickkopf (Dkk)-1 was initially discovered as a Wnt antagonist that plays an important role in head formation. By far, four m embers of Dkk have been identified in mammals. Each Dkk molecule contains two conserved cysteine-rich domain Numero articolo: BIOV3802R-100 Unità di misura: 100 MCG Imballaggio: Vial 309,00 CHF 309.0 CHF Aktuelle Lieferfrist auf Anfrage	Prohibitin is an evolutionarily conserved protein that has anti-proliferative activity. Prohibitin is a 30 kDa, post-synthetically modified protein found in the inner membrane of mitochondria and on the plasma membrane of B cells. Numero articolo: BIOV3805-100 Unità di misura: 100 MCG Imballaggio: Vial 309,00 CHF 309.0 CHF Aktuelle Lieferfrist auf Anfrage	Mitochondrial Trifunctional Protein (TFP) is a multienzyme complex of the beta-oxidation cycle. TFP deficiency is a clinically heter ogeneous disorder with phenotypes of different severity. The spectrum of diseases range from severe neonatal Numero articolo: BIOV3721-100 Unità di misura: 100 MCG Imballaggio: Vial 379,00 CHF 379.0 CHF Aktuelle Lieferfrist auf Anfrage
Catalase is known marker for peroxisomes. It is the most abundant protein in the peroxisomes. It is present in all aerobically resp iring organisms. It protects cells form the toxicity of hydrogen peroxide. Numero articolo: BIOV3806-100 Unità di misura: 100 MCG Imballaggio: Vial 309,00 CHF 309.0 CHF Aktuelle Lieferfrist auf Anfrage	uPAR (Urokinase plasminogen activator receptor) is a 55 kDa glycoprotein I-anchored surface receptor specific for urokinase plasmino gen activator (uPA). Upon binding to uPAR, uPA converts the surface bound, large serum β-globulin, plasminog Numero articolo: BIOV3722-100 Unità di misura: 100 MCG Imballaggio: Vial 309,00 CHF 309.0 CHF Aktuelle Lieferfrist auf Anfrage	The matrix metalloproteinases (MMP) are a family of peptidase enzymes responsible for the degradation of extracellular matrix compon ents, including collagen, gelatin, fibronectin, laminin and proteoglycan. Transcription of MMP genes is diff Numero articolo: BIOV3732-100 Unità di misura: 100 MCG Imballaggio: Vial 328,00 CHF 328.0 CHF Aktuelle Lieferfrist auf Anfrage	Hemopexin (HPX) is a plasma protein that has the highest binding affinity for heme. HPX prevents heme-mediated oxidative stress and heme-bound iron loss by transporting heme to the liver for breakdown. Numero articolo: BIOV3899-200 Unità di misura: 200 MCG Imballaggio: Vial 309,00 CHF 309.0 CHF Aktuelle Lieferfrist auf Anfrage
Lysosomal-associated membrane protein 2 (LAMP2) also known as CD107B (Cluster of Differentiation 107B) is a membrane glycoprotein. LAMP2 plays an important role in the normal function of lysosome which includes protecting lysosomal membran Numero articolo: BIOV3900-100 Unità di misura: 100 MCG Imballaggio: Vial 322,00 CHF 322.0 CHF Aktuelle Lieferfrist auf Anfrage	Comparative Gene Identification-58 (CGI-58) is a causal gene of Dorfman-Chanarin syndrome, a neutral lipid storage disease character ized by the presence of intracellular lipid droplets in tissues. CGI-58 comes from a large family of protein Numero articolo: BIOV3901-100 Unità di misura: 100 MCG Imballaggio: Vial 309,00 CHF 309.0 CHF Aktuelle Lieferfrist auf Anfrage	AS160 is a 160 kDa Akt serine/threonine kinase substrate that plays a critical role in regulating insulin-stimulated exocytosis of g lucose transporter GLUT4. Increased in insulin treatment stimulate phophorylation of AS160 Numero articolo: BIOV3954-100 Unità di misura: 100 MCG Imballaggio: Vial 309,00 CHF 309.0 CHF Aktuelle Lieferfrist auf Anfrage	Lactate dehydrogenase (LDH) contains two isoforms in mammals, LDH-M and LDH-H, which come together to form a homotetramer of 36 kDa subunits. LDH is often as a marker for tissue breakdown or cytotoxicity. LDH shows cytoplasm localization. Numero articolo: BIOV3842-500 Unità di misura: 500 MCG Imballaggio: Vial 284,00 CHF 284.0 CHF Aktuelle Lieferfrist auf Anfrage
Stearoyl-CoA desaturase (SCD) is a regulatory enzyme involved in the synthesis of oleate and palmitoleate. Oleate and palmitoleate a re the main components of membrane phospholipid, triglycerides and cholesterol esters. Numero articolo: BIOV3843-100 Unità di misura: 100 MCG Imballaggio: Vial 309,00 CHF 309.0 CHF Aktuelle Lieferfrist auf Anfrage	DMP-1 (Dentin matrix protein1) is a member of the integrin ligand N-linked glycoprotein family.It is mostly found in bone, tooth and hypertrophic cartilage. DMP-1 plays an important role in dentin and bone mineralization. DMP-1 has multiple Numero articolo: BIOV3844-100 Unità di misura: 100 MCG Imballaggio: Vial 354,00 CHF 354.0 CHF Aktuelle Lieferfrist auf Anfrage	The phosphodiesterase type-3 (PDE3) family is comprised of 2 isoforms, PDE3A and PDE3B.Phosphodiesterases (PDE) are crucial in the r egulation of the intracellular level of the second messenger cAMP by hydrolyzing cAMP to 5’AMP. Numero articolo: BIOV3956-200 Unità di misura: 200 MCG Imballaggio: Vial 309,00 CHF 309.0 CHF Aktuelle Lieferfrist auf Anfrage	Rictor is a component of a protein complex [mTORC2] that integrates nutrient- and growth factor-derived signals to regulate cell gro wth. Rictor also plays an essential role in Akt phosphorylation and signaling. Numero articolo: BIOV3957-200 Unità di misura: 200 MCG Imballaggio: Vial 309,00 CHF 309.0 CHF Aktuelle Lieferfrist auf Anfrage

VWR / Merck Prodotti chimici