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Elk-1 is a transcription factor that binds the serum response element (SRE) and mediates gene activity in response to serum and grow th factors. Elk-1 is phosphorylated by MAP kinase pathways and appears to be a direct target of activated MA Numero articolo: BIOV3387-100 Unità di misura: 100 MCG Imballaggio: Vial 335,00 CHF 335.0 CHF Aktuelle Lieferfrist auf Anfrage	Short/branched chain acyl-CoA dehydrogenase(ACADSB) belongs to the acyl-CoA dehydrogenase family of enzymes that catalyze the dehydr ogenation of acyl-CoA derivatives in the metabolism of fatty acids or branch chained amino acids. Numero articolo: BIOV3150-100 Unità di misura: 100 MCG Imballaggio: Vial 309,00 CHF 309.0 CHF Aktuelle Lieferfrist auf Anfrage	Heat shock proteins (HSPs) are ubiquitously expressed in all organisms. A major function of HSP90 and other HSPs is to act as molecu lar chaperones. HSP90 forms a complex with glucocorticoid receptor (GR), rendering the non ligand-bound rece Numero articolo: BIOV3389-100 Unità di misura: 100 MCG Imballaggio: Vial 354,00 CHF 354.0 CHF Aktuelle Lieferfrist auf Anfrage	Protein arginine methylation is a form of post-translational modification that is catalyzed by protein arginine methyltransferases ( PRMTs). PRMT6 catalyzes the sequential transfer of a methyl group from S-adenosyl-L-methionine to the side Numero articolo: BIOV3086-100 Unità di misura: 100 MCG Imballaggio: Vial 309,00 CHF 309.0 CHF Aktuelle Lieferfrist auf Anfrage
Hexokinases phosphorylate glucose to produce glucose-6-phosphate, thus committing glucose to the glycolytic pathway. Alternative spl icing of the gene for GCK results in three tissue-specific forms of glucokinase, one found in pancreatic isl Numero articolo: BIOV3154-100 Unità di misura: 100 MCG Imballaggio: Vial 410,00 CHF 410.0 CHF Aktuelle Lieferfrist auf Anfrage	Caspase family of cysteine proteases has been shown to play a key role in apoptosis. Similar to other caspases, caspase-6 is also sy nthesized as an inactive pro-enzyme that is processed in cells undergoing apoptosis. Numero articolo: BIOV3156-100 Unità di misura: 100 MCG Imballaggio: Vial 429,00 CHF 429.0 CHF Aktuelle Lieferfrist auf Anfrage	Short/branched chain acyl-CoA dehydrogenase(ACADSB) belongs to the acyl-CoA dehydrogenase family of enzymes catalyze the dehydrogena tion of acyl-CoA derivatives in the metabolism of fatty acids or branch chained amino acids. Numero articolo: BIOV3157-100 Unità di misura: 100 MCG Imballaggio: Vial 309,00 CHF 309.0 CHF Aktuelle Lieferfrist auf Anfrage	The MBD family of proteins includes MeCP2, MBD1, MBD2, MBD3 and MBD4. MBD2 is highly similar to MBD3 but only MBD2 targets the MeCP1 complex to methylate DNA. MBD2 has two isoforms, MBD2a and MBD2b. MBD2a is a 414 amino acids protein Numero articolo: BIOV3232-100 Unità di misura: 100 MCG Imballaggio: Vial 309,00 CHF 309.0 CHF Aktuelle Lieferfrist auf Anfrage
Heme oxygenase-1 (HO-1) or HSP32 is the inducible isoform of heme oxygenase which catalyzes the NADPH, O2 and cytochrome P450 reduct ase dependent oxidation of heme to carbon monoxide, iron and biliverdin that is immediately reduced to bilir Numero articolo: BIOV3391-100 Unità di misura: 100 MCG Imballaggio: Vial 354,00 CHF 354.0 CHF Aktuelle Lieferfrist auf Anfrage	TCTN1 belongs to the Tectonic protein family that regulate Hedgehog (Hh) pathway. During neural tube development, TCTN1 is required for the formation of most ventral cell types and for full Hh pathway activation. Numero articolo: BIOV3088-100 Unità di misura: 100 MCG Imballaggio: Vial 309,00 CHF 309.0 CHF Aktuelle Lieferfrist auf Anfrage	Bcl-xL is a 30 kDa anti-apoptotic protein belonging to the Bcl-2 family. Bcl-xL prevents apoptosis throμgh two different mechanisms: by heterodimerization with an apoptotic protein to inhibit its apoptotic effect, and by its direct pore-for Numero articolo: BIOV3312-100 Unità di misura: 100 MCG Imballaggio: Vial 360,00 CHF 360.0 CHF Aktuelle Lieferfrist auf Anfrage	Heme oxygenase (HO) is a microsomal enzyme that oxidatively cleaves heme, a pro-oxidant, into carbon monoxide and biliverdin. Two he me oxygenase isozymes, termed HO-1 and HO-2, have been identified so far. Numero articolo: BIOV3392-100 Unità di misura: 100 MCG Imballaggio: Vial 354,00 CHF 354.0 CHF Aktuelle Lieferfrist auf Anfrage
KLF4 belongs to the erythroid Kruppel-like factor (EKLF) family that is involved in the differentiation of epithelial cells and may also function in skeletal and kidney development. Numero articolo: BIOV3089-200 Unità di misura: 200 MCG Imballaggio: Vial 309,00 CHF 309.0 CHF Aktuelle Lieferfrist auf Anfrage	Cell death signal are transduced by death domain (DD), death effector domain (DED), and caspase recruitment domain (CARD) containing molecules. A novel protein that interacts with DED of caspase-8 and -10 Numero articolo: BIOV3313-100 Unità di misura: 100 MCG Imballaggio: Vial 335,00 CHF 335.0 CHF Aktuelle Lieferfrist auf Anfrage	Heterodimers between TCF3 and tissue specific basic helix loop helix (bHLH) proteins play important roles in determining tissue spec ific cell fate during embryogenesis, like muscle or early B cell differentiation. Numero articolo: BIOV3090-100 Unità di misura: 100 MCG Imballaggio: Vial 309,00 CHF 309.0 CHF Aktuelle Lieferfrist auf Anfrage	PTP1B is the founding member of the protein tyrosine phosphatase (PTP) family, which was isolated and identified based on its enzyma tic activity and amino acid sequence. PTPs catalyze the hydrolysis of the phosphate monoesters specifically Numero articolo: BIOV3171-100 Unità di misura: 100 MCG Imballaggio: Vial 410,00 CHF 410.0 CHF Aktuelle Lieferfrist auf Anfrage
Erk-5 shares high homology in the amino-terminal kinase domain with Erk1/2. However, the long carboxy-terminal kinase domain makes E rk5 a unique MAP kinase. Erk5 is activated by a variety of extracellular signals. The direct upstream kinase Numero articolo: BIOV3397-100 Unità di misura: 100 MCG Imballaggio: Vial 335,00 CHF 335.0 CHF Aktuelle Lieferfrist auf Anfrage	NF-kB is silenced in the cytoplasm by an inhibitory protein, IkB. IkB proteins are phosphorylated by IkB kinase complex consisting o f at least three proteins, IKK1/α, IKK2/β, and IKK3/g. External stimuli such TNF-α or other cytokines result Numero articolo: BIOV3315-100 Unità di misura: 100 MCG Imballaggio: Vial 373,00 CHF 373.0 CHF Aktuelle Lieferfrist auf Anfrage	Fas (APO-1, CD95) is a 45 kDa cell surface protein that mediates apoptosis when cross-linked with agonistic anti-Fas antibodies or F as ligand (FasL). FasL is a tumor necrosis factor (TNF)-related type II membrane protein and is expressed in Numero articolo: BIOV3330-100 Unità di misura: 100 MCG Imballaggio: Vial 373,00 CHF 373.0 CHF Aktuelle Lieferfrist auf Anfrage	LIN28 is a highly conserved cytoplasmic RNAbinding protein. Lin28 has an N-terminal cold shock domain and two Cterminal (CCHC) zin c finger motif. It is expressed in embryonic stem cells and embryonic carcinoma cells. Numero articolo: BIOV3091-200 Unità di misura: 200 MCG Imballaggio: Vial 309,00 CHF 309.0 CHF Aktuelle Lieferfrist auf Anfrage

VWR / Merck Prodotti chimici