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PKC (Protein kinase C) is a calcium-dependent and phospholipid-dependent enzyme that is activated in vivo by the lipid diacylglycero l. PKC has been shown to be involved in signal transduction and various aspects of neoplastic transformation Numero articolo: BIOV3451-100 Unità di misura: 100 MCG Imballaggio: Vial 410,00 CHF 410.0 CHF Aktuelle Lieferfrist auf Anfrage	Human p21-GTPase-activated protein kinase 1 (PAK1) is a functional homolog of STE20 of Saccharomyces cerevisiae. PAK1 is a downstrea m effector of the Rho-family small GTPases Rac and Cdc42. A serine/threonine kinase Numero articolo: BIOV3248-100 Unità di misura: 100 MCG Imballaggio: Vial 335,00 CHF 335.0 CHF Aktuelle Lieferfrist auf Anfrage	PKGs are cyclic GMP-dependent protein kinases (also designed cGKs) that are classified into two types, PKGI and PKGII. Studies have shown that cGKs and cyclic AMP-dependent kinases (cAKs) are highly homologous protein kinase families Numero articolo: BIOV3452-100 Unità di misura: 100 MCG Imballaggio: Vial 335,00 CHF 335.0 CHF Aktuelle Lieferfrist auf Anfrage	Tau, a microtubule-binding protein which serves to stabilize microtubules in growing axons, is found to be hyperphosphorylated in pa ired helical filaments (PHF), the major fibrous component of neurofibrillary lesions associated with Alzheim Numero articolo: BIOV3453-100 Unità di misura: 100 4G Imballaggio: Vial 455,00 CHF 455.0 CHF Aktuelle Lieferfrist auf Anfrage
IkB-alpha protein is a NF-kB inhibitory protein. It binds NF-kB and retains the complex in the cytoplasm, thereby preventing it from entering into nucleus and functioning as a transcription factor. Upon receiving a variety of signals, IkB-a Numero articolo: BIOV3252-100 Unità di misura: 100 MCG Imballaggio: Vial 309,00 CHF 309.0 CHF Aktuelle Lieferfrist auf Anfrage	Serum and glucocorticoid-inducible kinase (SGK) is a serine/threonine kinase that is closely related to Akt. SGK is rapidly induced in response to a variety of stimuli, including serum, hormones, and osmotic shock, etc. Numero articolo: BIOV3459-100 Unità di misura: 100 MCG Imballaggio: Vial 309,00 CHF 309.0 CHF Aktuelle Lieferfrist auf Anfrage	ACAA2 (acetylcoenzyme A acyltransferase 2), is member of the thiolase family of enzymes and is involved in lipid metabolism. ACAA2 i s localized in the mitochondria. ACCA2 catalyzes the last conversion step of acetyl-CoA to 3-oxoacyl-CoA, in Numero articolo: BIOV3538-100 Unità di misura: 100 MCG Imballaggio: Vial 309,00 CHF 309.0 CHF Aktuelle Lieferfrist auf Anfrage	Smad proteins, the mammalian homologs of the Drosophila Mothers against dpp (Mad), have been implicated as downstream effectors of T GFβ/BMP signaling. Smad1, Smad5, and Smad8 are effectors of BMP2 and BMP4 function Numero articolo: BIOV3461-100 Unità di misura: 100 MCG Imballaggio: Vial 335,00 CHF 335.0 CHF Aktuelle Lieferfrist auf Anfrage
The cathepsin family of proteolytic enzymes contains several diverse classes of proteases. The cysteine protease class comprises cat hepsins B, L, H, K, S, and O. The aspartyl protease class is composed of cathepsins D and E. Numero articolo: BIOV3412-100 Unità di misura: 100 MCG Imballaggio: Vial 373,00 CHF 373.0 CHF Aktuelle Lieferfrist auf Anfrage	Smad proteins, the mammalian homologs of the Drosophila Mothers against dpp (Mad), have been implicated as downstream effectors of T GFβ/BMP signaling. Smad1, Smad5, and Smad8 are effectors of BMP2 and BMP4 function Numero articolo: BIOV3464-100 Unità di misura: 100 MCG Imballaggio: Vial 309,00 CHF 309.0 CHF Aktuelle Lieferfrist auf Anfrage	Smad proteins, the mammalian homologs of the Drosophila Mothers against dpp (Mad), have been implicated as downstream effectors of T GFβ/BMP signaling. Smad1, Smad5, and Smad8 are effectors of BMP2 and BMP4 function Numero articolo: BIOV3465-100 Unità di misura: 100 MCG Imballaggio: Vial 335,00 CHF 335.0 CHF Aktuelle Lieferfrist auf Anfrage	GADD153 has been described as a growth arrest and DNA damage-inducible gene that encodes a C/EBP-related nuclear protein. Expression of GADD153 is induced by a variety of cellular stresses Numero articolo: BIOV3421-100 Unità di misura: 100 MCG Imballaggio: Vial 335,00 CHF 335.0 CHF Aktuelle Lieferfrist auf Anfrage
Membrane receptor signaling by various ligands induces activation of Jak kinases which then leads to tyrosine phosphorylation of the various Stat transcription factors. Stat1 and Stat2 are induced by IFN-α and form a heterodimer Numero articolo: BIOV3468R-100 Unità di misura: 100 MCG Imballaggio: Vial 309,00 CHF 309.0 CHF Aktuelle Lieferfrist auf Anfrage	Cell adhesion molecules (CAMs) are a family of closely related cell surface glycoproteins involved in cell-cell interactions during growth and are thoμght to play an important role in embryogenesis and development. The family contains NCAM Numero articolo: BIOV3422R-100 Unità di misura: 100 MCG Imballaggio: Vial 354,00 CHF 354.0 CHF Aktuelle Lieferfrist auf Anfrage	Nuclear factor kappa B (NFkB) was identified as a sequence specific transcriptional activator that binds to the intronic enhancer of kappa light chain gene in B lymphocytes. NFkB is a heterodimer that consists of a 50 kDa DNA binding subuni Numero articolo: BIOV3354R-100 Unità di misura: 100 MCG Imballaggio: Vial 309,00 CHF 309.0 CHF Aktuelle Lieferfrist auf Anfrage	Membrane receptor signaling by various ligands induces activation of Jak kinases which then leads to tyrosine phosphorylation of the various Stat transcription factors. Stat1 and Stat2 are induced by IFN-α and form a heterodimer Numero articolo: BIOV3469-100 Unità di misura: 100 MCG Imballaggio: Vial 410,00 CHF 410.0 CHF Aktuelle Lieferfrist auf Anfrage
Proteinase inhibitor 9 (PI-9, also designated cytoplasmic antiproteinase 3, or CAP3) is a 42 kDa member of the ovalbumin family of s erpins that is expressed in placenta, lung and cytotoxic lymphocytes. PI-9 is a potent inhibitor of granzyme Numero articolo: BIOV3544-100 Unità di misura: 100 MCG Imballaggio: Vial 373,00 CHF 373.0 CHF Aktuelle Lieferfrist auf Anfrage	RSKs (90 kDa family of ribosomal S6 kinases), designated Rsk-1, Rsk-2 and Rsk-3, have been implicated as important signaling interme diates in response to a broad range of ligand-activated receptor tyrosine kinases. Numero articolo: BIOV3546-100 Unità di misura: 100 MCG Imballaggio: Vial 335,00 CHF 335.0 CHF Aktuelle Lieferfrist auf Anfrage	URIDINE-5'-DIPHOSPHOGLUCOSEDISODIUM--N/H Numero articolo: ICNA0210120890 Unità di misura: 500 MG Imballaggio: bottle 444,00 CHF 444.0 CHF Aktuelle Lieferfrist auf Anfrage	NPM (Nucleophosmin) is an abundant phosphoprotein primarily found in nucleoli. It has been implicated in several distinct cellular f unctions, including assembly and transport of ribosomes, cytoplasmic/nuclear trafficking, regulation of DNA Numero articolo: BIOV3425-100 Unità di misura: 100 MCG Imballaggio: Vial 335,00 CHF 335.0 CHF Aktuelle Lieferfrist auf Anfrage

VWR / Merck Prodotti chimici