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VWR / Merck Prodotti chimici
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VWR / Merck Prodotti chimici
p53, a 53 kDa protein, binds to a DNA consensus sequence, the p53 response element, and regulates normal cell cycle events by activa ting transcription of genes involved either in progression throμgh the cell cycle
Numero articolo:
BIOV3036R-100
Unità di misura:
100 MCG
Imballaggio:
Vial
309,00
CHF
309.0
CHF
Aktuelle Lieferfrist auf Anfrage
AMPKα (PRKAA1) belongs to the ser/thr protein kinase family. It is the catalytic subunit of the 5'-prime-AMP-activated protein kinas e (AMPK). AMPK is a cellular energy sensor conserved in all eukaryotic cells.
Numero articolo:
BIOV3113-100
Unità di misura:
100 MCG
Imballaggio:
Vial
410,00
CHF
410.0
CHF
Aktuelle Lieferfrist auf Anfrage
Caspase family of cysteine proteases plays a key role in apoptosis. Caspase-9 is one of the most important caspases among the caspas e family members.
Numero articolo:
BIOV3037-100
Unità di misura:
100 MCG
Imballaggio:
Vial
309,00
CHF
309.0
CHF
Aktuelle Lieferfrist auf Anfrage
Akt, also referred to as PKB and RAC, is the cellular homologue of the viral oncogene v-Akt. This protein kinase is activated by ins ulin and various growth factors and functions in a pathway involving PI3 kinase as activation is sensitive t
Numero articolo:
BIOV3257-100
Unità di misura:
100 MCG
Imballaggio:
Vial
429,00
CHF
429.0
CHF
Aktuelle Lieferfrist auf Anfrage
Caspase-8, a member of the caspase-family of proteases, plays a key role in mediating Fas (CD95) and TNF induced apoptosis. Caspase- 8 is synthesized as inactive pro-enzyme and activation of the enzyme involves proteolytic cleavage that lead
Numero articolo:
BIOV3258-100
Unità di misura:
100 MCG
Imballaggio:
Vial
442,00
CHF
442.0
CHF
Aktuelle Lieferfrist auf Anfrage
The precursor of cytochrome c, apocytochrome c, is synthesized in the cytoplasm. Upon translocation into mitochondria, cytochrome c acquires a heme moiety required for functionality in the mitochondrial respiration chain.
Numero articolo:
BIOV3187-100
Unità di misura:
100 MCG
Imballaggio:
Vial
410,00
CHF
410.0
CHF
Aktuelle Lieferfrist auf Anfrage
Human perforin (cytolysin) is believed to be one of the major effector molecules used by cytotoxic T cells and NK cells to mediate t argeted cell lysis. Perforin expression is constitutive on NK cells, but increases in resting XD8+ cytotoxic
Numero articolo:
BIOV3188R-100
Unità di misura:
100 MCG
Imballaggio:
Vial
309,00
CHF
309.0
CHF
Aktuelle Lieferfrist auf Anfrage
Caspase-8, a member of the caspase-family of proteases, plays a key role in mediating Fas (CD95) and TNF induced apoptosis. Caspase- 8 is synthesized as inactive pro-enzyme and activation of the enzyme involves proteolytic cleavage that lead
Numero articolo:
BIOV3259-100
Unità di misura:
100 MCG
Imballaggio:
Vial
335,00
CHF
335.0
CHF
Aktuelle Lieferfrist auf Anfrage
Protein kinase A (PKA) also known as cAMP-dependent protein kinase, is a 40 kDa protein kinase that phosphorylates serine or threoni ne residues in target proteins in response to elevated levels of cAMP. It has been sμggested that the comple
Numero articolo:
BIOV3115-100
Unità di misura:
100 MCG
Imballaggio:
Vial
309,00
CHF
309.0
CHF
Aktuelle Lieferfrist auf Anfrage
PARD (partitioning-defective) proteins are important in asymmetric cell division and polarized growth. PARD3 plays a vital role in t he formation of epithelial tight junctions. The PARD6-PARD3 complex links GTP-bound Rho small GTPases
Numero articolo:
BIOV3260-100
Unità di misura:
100 MCG
Imballaggio:
Vial
309,00
CHF
309.0
CHF
Aktuelle Lieferfrist auf Anfrage
Calpains are cytosolic, calcium-dependent, cysteine proteases that are ubiquitously expressed in mammalian and avian tissues. Type I calpain requires micromolar amounts of calcium, while type II calpain requires millimolar amounts of calciu
Numero articolo:
BIOV3189-100
Unità di misura:
100 MCG
Imballaggio:
Vial
309,00
CHF
309.0
CHF
Aktuelle Lieferfrist auf Anfrage
InSolution GSK-3 Inhibitor XVI CHIR99021
Numero articolo:
361571-5MG
Unità di misura:
5 MG
Imballaggio:
Glass bottle
607,00
CHF
607.0
CHF
Aktuelle Lieferfrist auf Anfrage
Death Associated Protein 1 (DAP1) is a 15 kDa protein that functions as a positive mediator of cell death initiated by interferon-ga mma. The DAP1 protein is praline-rich and possesses one SH3 binding motif, as well as several consensus prot
Numero articolo:
BIOV3261-100
Unità di misura:
100 MCG
Imballaggio:
Vial
360,00
CHF
360.0
CHF
Aktuelle Lieferfrist auf Anfrage
TCTN2 is a member of the Tectonic protein family. Tectonic proteins are transmembrane proteins that regulate the Hedgehog (Hh)-signa ling pathway. Defects in TCTN2 can lead to Meckel syndrome type 8. This disorder is characterized by a comb
Numero articolo:
BIOV3262-100
Unità di misura:
100 MCG
Imballaggio:
Vial
309,00
CHF
309.0
CHF
Aktuelle Lieferfrist auf Anfrage
The protein encoded by this gene is a catalytic subunit of the AMP-activated protein kinase (AMPK). AMPK is a heterotrimer consistin g of an alpha catalytic subunit, and non-catalytic beta and gamma subunits. AMPK is an important energy-sens
Numero articolo:
BIOV3117-100
Unità di misura:
100 MCG
Imballaggio:
Vial
410,00
CHF
410.0
CHF
Aktuelle Lieferfrist auf Anfrage
The caspase family of cysteine proteases play a key role in apoptosis. Caspase-3 is the most extensively studied apoptotic protein a mong caspase family members.
Numero articolo:
BIOV3004-100
Unità di misura:
100 MCG
Imballaggio:
Vial
391,00
CHF
391.0
CHF
Aktuelle Lieferfrist auf Anfrage
Cathepsin D is a normal lysosomal protease that is expressed in all cells. It is an aspartyl protease with a pH optimum in the range of 3-5, and contains two N-linked oligosaccharides. Cathepsin D is synthesized as an inactive 52 kDa pro
Numero articolo:
BIOV3191R-100
Unità di misura:
100 MCG
Imballaggio:
Vial
322,00
CHF
322.0
CHF
Aktuelle Lieferfrist auf Anfrage
Fodrin is a universally expressed membrane-associated cytoskeletal protein consisting of α- and β-subunits. The protein is important for maintaining normal membrane structure and supporting cell surface protein function. α-Fodrin is one of
Numero articolo:
BIOV3266-100
Unità di misura:
100 MCG
Imballaggio:
Vial
309,00
CHF
309.0
CHF
Aktuelle Lieferfrist auf Anfrage
Cathepsin L is a normal lysosomal cysteine endoproteases that is expressed in all cells. The latent 39 kDa pro-Cathepsin L must be p rocessed by cleavage of the 96 amino acid pro-peptide, to generate the active two-chain form made up of 21
Numero articolo:
BIOV3192-100
Unità di misura:
100 MCG
Imballaggio:
Vial
322,00
CHF
322.0
CHF
Aktuelle Lieferfrist auf Anfrage
Wee1 is a nuclear tyrosine protein kinase. The protein plays a role in suppressing eukaryotes’ entry into mitosis by inactivating cd c2 kinase by inhibiting tyrosine phosphorylation. The predicted molecular weight of the kinase is 72 kDa.
Numero articolo:
BIOV3120-100
Unità di misura:
100 MCG
Imballaggio:
Vial
335,00
CHF
335.0
CHF
Aktuelle Lieferfrist auf Anfrage
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