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IkB-alpha protein is a NF-kB inhibitory protein. It binds NF-kB and retains the complex in the cytoplasm, thereby preventing it from entering into nucleus and functioning as a transcription factor. Upon receiving a variety of signals, IkB-a Numero articolo: BIOV3252-100 Unità di misura: 100 MCG Imballaggio: Vial 309,00 CHF 309.0 CHF Tempo di consegna attuale su richiesta	Serum and glucocorticoid-inducible kinase (SGK) is a serine/threonine kinase that is closely related to Akt. SGK is rapidly induced in response to a variety of stimuli, including serum, hormones, and osmotic shock, etc. Numero articolo: BIOV3459-100 Unità di misura: 100 MCG Imballaggio: Vial 309,00 CHF 309.0 CHF Tempo di consegna attuale su richiesta	ACAA2 (acetylcoenzyme A acyltransferase 2), is member of the thiolase family of enzymes and is involved in lipid metabolism. ACAA2 i s localized in the mitochondria. ACCA2 catalyzes the last conversion step of acetyl-CoA to 3-oxoacyl-CoA, in Numero articolo: BIOV3538-100 Unità di misura: 100 MCG Imballaggio: Vial 309,00 CHF 309.0 CHF Tempo di consegna attuale su richiesta	Chemokines play important roles in inflammation and critical for the recruitment of effector immune cells to sites of infection. Che mokines activate leukocytes by binding to G protein coupled receptors. Numero articolo: BIOV3419-100 Unità di misura: 100 MCG Imballaggio: Vial 309,00 CHF 309.0 CHF Tempo di consegna attuale su richiesta
Cytochrome c (m.w. 12,500) is an electron transport protein from mitochondria. It is released from mitochondria to cytoplasm during the early stages of apoptosis, prior to caspase activation, DNA fragmentation, and loss of membrane potentia Numero articolo: BIOV3352-100 Unità di misura: 100 MCG Imballaggio: Vial 309,00 CHF 309.0 CHF Tempo di consegna attuale su richiesta	Smad proteins, the mammalian homologs of the Drosophila Mothers against dpp (Mad), have been implicated as downstream effectors of T GFβ/BMP signaling. Smad1, Smad5, and Smad8 are effectors of BMP2 and BMP4 function Numero articolo: BIOV3461-100 Unità di misura: 100 MCG Imballaggio: Vial 335,00 CHF 335.0 CHF Tempo di consegna attuale su richiesta	Chemokines play important roles in inflammation and critical for the recruitment of effector immune cells to sites of infection. Che mokines activate leukocytes by binding to G protein coupled receptors. Numero articolo: BIOV3416R-100 Unità di misura: 100 MCG Imballaggio: Vial 309,00 CHF 309.0 CHF Tempo di consegna attuale su richiesta	The cathepsin family of proteolytic enzymes contains several diverse classes of proteases. The cysteine protease class comprises cat hepsins B, L, H, K, S, and O. The aspartyl protease class is composed of cathepsins D and E. Numero articolo: BIOV3412-100 Unità di misura: 100 MCG Imballaggio: Vial 373,00 CHF 373.0 CHF Tempo di consegna attuale su richiesta
Smad proteins, the mammalian homologs of the Drosophila Mothers against dpp (Mad), have been implicated as downstream effectors of T GFβ/BMP signaling. Smad1, Smad5, and Smad8 are effectors of BMP2 and BMP4 function Numero articolo: BIOV3464-100 Unità di misura: 100 MCG Imballaggio: Vial 309,00 CHF 309.0 CHF Tempo di consegna attuale su richiesta	Gαi2 is a 40-41 kDa alpha-subunit of heterotrimeric protein that shares sequence homology with Gαi3 and Gαi1. All these G proteins c an be ADP-ribosylated at the carboxy terminal Cys of the CAAX sequence, interfering with receptor coupling. Numero articolo: BIOV3249-100 Unità di misura: 100 MCG Imballaggio: Vial 309,00 CHF 309.0 CHF Tempo di consegna attuale su richiesta	It has been proposed that high density lipoproteins (HDLs) function jointly with lecithin:cholesterol acyltransferase and CETP to fa cilitate cholesterol transport from tissues to the liver. CETP is responsible for neutral lipid transfer act Numero articolo: BIOV3413-100 Unità di misura: 100 MCG Imballaggio: Vial 354,00 CHF 354.0 CHF Tempo di consegna attuale su richiesta	Cytochrome c (m.w. 12,500) is an electron transport protein from mitochondria. It is released from mitochondria to cytoplasm during the early stages of apoptosis, prior to caspase activation, DNA fragmentation, and loss of membrane potentia Numero articolo: BIOV3353-100 Unità di misura: 100 MCG Imballaggio: Vial 309,00 CHF 309.0 CHF Tempo di consegna attuale su richiesta
Smad proteins, the mammalian homologs of the Drosophila Mothers against dpp (Mad), have been implicated as downstream effectors of T GFβ/BMP signaling. Smad1, Smad5, and Smad8 are effectors of BMP2 and BMP4 function Numero articolo: BIOV3465-100 Unità di misura: 100 MCG Imballaggio: Vial 335,00 CHF 335.0 CHF Tempo di consegna attuale su richiesta	GADD153 has been described as a growth arrest and DNA damage-inducible gene that encodes a C/EBP-related nuclear protein. Expression of GADD153 is induced by a variety of cellular stresses Numero articolo: BIOV3421-100 Unità di misura: 100 MCG Imballaggio: Vial 335,00 CHF 335.0 CHF Tempo di consegna attuale su richiesta	Syntaxins were originally thoμght to be docking proteins, but have more recently been categorized as anchoring proteins that anchor themselves to the cytoplasmic surfaces of cellular membranes. Syntaxins have been shown to bind to various p Numero articolo: BIOV3541-100 Unità di misura: 100 MCG Imballaggio: Vial 309,00 CHF 309.0 CHF Tempo di consegna attuale su richiesta	Caspase-6 is one of the major executioner caspases functioning in cellular apoptotic processes. Similar as other caspases, caspase-6 is also synthesized as an inactive pro-enzyme that is processed in cells undergoing apoptosis. Numero articolo: BIOV3256-100 Unità di misura: 100 MCG Imballaggio: Vial 309,00 CHF 309.0 CHF Tempo di consegna attuale su richiesta
Membrane receptor signaling by various ligands induces activation of Jak kinases which then leads to tyrosine phosphorylation of the various Stat transcription factors. Stat1 and Stat2 are induced by IFN-α and form a heterodimer Numero articolo: BIOV3468R-100 Unità di misura: 100 MCG Imballaggio: Vial 309,00 CHF 309.0 CHF Tempo di consegna attuale su richiesta	Cell adhesion molecules (CAMs) are a family of closely related cell surface glycoproteins involved in cell-cell interactions during growth and are thoμght to play an important role in embryogenesis and development. The family contains NCAM Numero articolo: BIOV3422R-100 Unità di misura: 100 MCG Imballaggio: Vial 354,00 CHF 354.0 CHF Tempo di consegna attuale su richiesta	Nuclear factor kappa B (NFkB) was identified as a sequence specific transcriptional activator that binds to the intronic enhancer of kappa light chain gene in B lymphocytes. NFkB is a heterodimer that consists of a 50 kDa DNA binding subuni Numero articolo: BIOV3354R-100 Unità di misura: 100 MCG Imballaggio: Vial 309,00 CHF 309.0 CHF Tempo di consegna attuale su richiesta	Membrane receptor signaling by various ligands induces activation of Jak kinases which then leads to tyrosine phosphorylation of the various Stat transcription factors. Stat1 and Stat2 are induced by IFN-α and form a heterodimer Numero articolo: BIOV3469-100 Unità di misura: 100 MCG Imballaggio: Vial 410,00 CHF 410.0 CHF Tempo di consegna attuale su richiesta

VWR / Merck Prodotti chimici