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JMJD1C is a member of the jumonji (jmj) domain containing gene family of histone demethylases that plays a role in chromatin regulat ion and influences transcriptional activation and suppression. Numero articolo: BIOV3439-100 Unità di misura: 100 MCG Imballaggio: Vial 335,00 CHF 335.0 CHF Tempo di consegna attuale su richiesta	Rab5 is a 24 kDa GTP-binding protein that is localized to the cytoplasmic side of the plasma membrane, clathrin-coated vesicles, and early endosomes. Rab5 is believed to regulate vesicle fusion throμgh a cycle of GDP/GTP exchange and GTP hy Numero articolo: BIOV3483-100 Unità di misura: 100 MCG Imballaggio: Vial 335,00 CHF 335.0 CHF Tempo di consegna attuale su richiesta	POLY-L-LYSINE HBR (MW 4,000 -15,000) Numero articolo: ICNA0210269191 Unità di misura: 1 G Imballaggio: Amber Glass Bottle 2.180,00 CHF 2180.0 CHF Tempo di consegna attuale su richiesta	The Toll-like receptor (TLR) family in mammalian comprises a family of transmembrane proteins characterized by multiple copies of le ucine rich repeats in the extracellular domain and IL-1 receptor motif in the cytoplasmic domain. Numero articolo: BIOV3558R-100 Unità di misura: 100 MCG Imballaggio: Vial 309,00 CHF 309.0 CHF Tempo di consegna attuale su richiesta
Tumor Endothelial Markers (TEMs, TEM 1-9) are recently identified genes, whose expression is elevated in tumor-associated endotheliu m. TEMs are barely detectable in normal endothelial cells. TEM8 has been shown to interact with C5 domain of Numero articolo: BIOV3668-100 Unità di misura: 100 MCG Imballaggio: Vial 309,00 CHF 309.0 CHF Tempo di consegna attuale su richiesta	HDAC family are divided into two classes, I and II. Class I of the HDAC family comprises four members, HDAC-1, 2, 3, and 8. Class II of the HDAC family comprises HDAC-4, 5, 6, and 7, the molecular weights of which are all about two-fold lar Numero articolo: BIOV3610-100 Unità di misura: 100 MCG Imballaggio: Vial 335,00 CHF 335.0 CHF Tempo di consegna attuale su richiesta	The Toll-like receptor (TLR) family of proteins are characterized by a highly conserved Toll homology (TH) domain, which is essentia l for Toll-induced signal transduction. TLR9 has been sμggested as a receptor for unmethylated CpG dinucleot Numero articolo: BIOV3559R-100 Unità di misura: 100 MCG Imballaggio: Vial 309,00 CHF 309.0 CHF Tempo di consegna attuale su richiesta	uPAR (Urokinase plasminogen activator receptor) is a 55 kDa glycoprotein I-anchored surface receptor specific for urokinase plasmino gen activator (uPA). Upon binding to uPAR, uPA converts the surface bound, large serum β-globulin, plasminog Numero articolo: BIOV3440-100 Unità di misura: 100 MCG Imballaggio: Vial 373,00 CHF 373.0 CHF Tempo di consegna attuale su richiesta
p70 S6 kinase and p90 Rsk kinase are the two distinct 40S ribosomal protein S6 Ser/Thr kinases present in somatic animal cells. p90 Rsk kinase is maximally activated within minutes of addition of growth factors or phorbol ester to cultured Numero articolo: BIOV3485-100 Unità di misura: 100 MCG Imballaggio: Vial 335,00 CHF 335.0 CHF Tempo di consegna attuale su richiesta	Both p44 and p42 MAP kinases (Erk1 and Erk2) function in a protein kinase cascade that plays a critical role in the regulation of ce ll growth and differentiation. Activation of MAP kinases occurs throμgh phosphorylation of threonine and tyr Numero articolo: BIOV3441-100 Unità di misura: 100 MCG Imballaggio: Vial 410,00 CHF 410.0 CHF Tempo di consegna attuale su richiesta	Cystatin A (acid cysteine proteinase inhibitor, ACPI) is a natural inhibitor of cysteine proteinases and is located mainly in the ke ratohyaline granules of the stratum granulosum and the cornified envelope of the stratum corneum in the epid Numero articolo: BIOV3486-100 Unità di misura: 100 MCG Imballaggio: Vial 373,00 CHF 373.0 CHF Tempo di consegna attuale su richiesta	Both p44 and p42 MAP kinases (Erk1 and Erk2) function in a protein kinase cascade that plays a critical role in the regulation of ce ll growth and differentiation. Activation of MAP kinases occurs throμgh phosphorylation of threonine and tyr Numero articolo: BIOV3442-100 Unità di misura: 100 MCG Imballaggio: Vial 335,00 CHF 335.0 CHF Tempo di consegna attuale su richiesta
Tyrosine hydroxylase (TH) is the rate-limiting enzyme in the synthesis of the catecholamines Dopamine and Norepinephrine. TH antibod ies can therefore be used as markers for dopaminergic and noradrenergic neurons in a variety of applications Numero articolo: BIOV3612-100 Unità di misura: 100 4G Imballaggio: Vial 448,00 CHF 448.0 CHF Tempo di consegna attuale su richiesta	Cystatin B (stefin B, NCPI) is a natural inhibitor of lysosomal cysteine proteases (cathepsins). Its expression seems to be connecte d to the regulation of proteolysis which is essential for many physiological and pathological processes. Numero articolo: BIOV3487-100 Unità di misura: 100 MCG Imballaggio: Vial 373,00 CHF 373.0 CHF Tempo di consegna attuale su richiesta	The PAK (p21-activated kinase) family of serine/threonine kinases plays an important role in multiple cellular processes, including cytoskeletal reorganization, MAPK signaling, apoptotic signaling, etc. Binding of Rac/cdc42 to the CRIB (or Numero articolo: BIOV3443-100 Unità di misura: 100 MCG Imballaggio: Vial 309,00 CHF 309.0 CHF Tempo di consegna attuale su richiesta	TRADD (TNF-R1-associated death domain) is a 34 kDa protein that associates with the death domains of both FAS and TNF-R1 via their D DH regions. Overexpression of TRADD leads to NFκB activation and apoptosis in the absence of TNF. Numero articolo: BIOV3561-100 Unità di misura: 100 MCG Imballaggio: Vial 309,00 CHF 309.0 CHF Tempo di consegna attuale su richiesta
Tyrosine hydroxylase (TH) is the rate-limiting enzyme in the synthesis of the catecholamines dopamine and norepinephrine. TH antibod ies can therefore be used as markers for dopaminergic and noradrenergic neurons in a variety of applications Numero articolo: BIOV3613-100 Unità di misura: 100 4G Imballaggio: Vial 448,00 CHF 448.0 CHF Tempo di consegna attuale su richiesta	Human EG-VEGF (Endocrine-gland-derived vascular endothelial growth factor) is a 9.6 kDa protein consisting of 86 amino acid residues . Human EG-VEGF induces proliferation, migration and fenestration in capillary endothelial cells derived fro Numero articolo: BIOV3489-100 Unità di misura: 100 4G Imballaggio: Vial 335,00 CHF 335.0 CHF Tempo di consegna attuale su richiesta	Methylation of DNA at cytosine residues plays an important role in regulation of gene expression, genomic imprinting and is essentia l for mammalian development. Hypermethylation of CpG islands in tumor suppressor genes or hypomethylation of Numero articolo: BIOV3488-100 Unità di misura: 100 MCG Imballaggio: Vial 335,00 CHF 335.0 CHF Tempo di consegna attuale su richiesta	Mammalian forkhead members of the class O (FOXO) transcription factors, including FOXO1, FOXO3a, and FOXO4, are implicated in the re gulation of a variety of cellular processes, including the cell cycle, apoptosis, DNA repair, stress resist Numero articolo: BIOV3673-100 Unità di misura: 100 MCG Imballaggio: Vial 309,00 CHF 309.0 CHF Tempo di consegna attuale su richiesta

VWR / Merck Prodotti chimici