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Members of the Bcl-2 family of proteins interact to regulate programmed cell death, or apoptosis. Various homodimers and heterodimer s formed by proteins in this family can either promote or inhibit apoptosis. Numero articolo: BIOV3176-100 Unità di misura: 100 MCG Imballaggio: Vial 360,00 CHF 360.0 CHF Tempo di consegna attuale su richiesta	PDK1 (Phosphoinositide-dependent protein kinase 1) plays an important role in cell signaling pathways and is involved in regulation of a wide variety of processes, including cell proliferation, differentiation and apoptosis. Numero articolo: BIOV3449-100 Unità di misura: 100 MCG Imballaggio: Vial 322,00 CHF 322.0 CHF Tempo di consegna attuale su richiesta	The synaptotagmins are integral membrane proteins of synaptic vesicles thoμght to serve as Ca (2+) sensors in the process of vesicul ar trafficking and exocytosis. Calcium binding to synaptotagmin participates in triggering neurotransmitter Numero articolo: BIOV3177-100 Unità di misura: 100 MCG Imballaggio: Vial 335,00 CHF 335.0 CHF Tempo di consegna attuale su richiesta	p53DINP1 (p53-dependent damage-inducible nuclear protein 1) encodes two proteins termed p53DINP1-α (27 kDa) and p53DINP1-β (18 kDa). p53DINP1 may regulate p53-dependent apoptosis throμgh phosphorylation at Ser46 and induction of p53AIP1. p5 Numero articolo: BIOV3340-100 Unità di misura: 100 MCG Imballaggio: Vial 322,00 CHF 322.0 CHF Tempo di consegna attuale su richiesta
Caspase-9 is one of the most important caspases among the caspase family members. Upon induction of apoptosis, cytochrome c released from mitochondria associates with procaspase-9/Apaf-1. Numero articolo: BIOV3409-100 Unità di misura: 100 MCG Imballaggio: Vial 309,00 CHF 309.0 CHF Tempo di consegna attuale su richiesta	HADH (Hydroxyacyl-Coenzyme A dehydrogenase) is a mitochondrial protein that catalyzes the oxidation of a wide variety of fatty acids , alcohols, and steroids. 3-hydroxyacyl-CoA dehydrogenase type II (HADH2) is a member of the short-chain deh Numero articolo: BIOV3246-100 Unità di misura: 100 MCG Imballaggio: Vial 309,00 CHF 309.0 CHF Tempo di consegna attuale su richiesta	Members of Oct family of transcription factors specifically interact with Octamer motif ATGCAAAT, a regulatory element important for tissue- and cell-specific transcription as well as for transcription of a number of housekeeping genes. All Numero articolo: BIOV3342-100 Unità di misura: 100 MCG Imballaggio: Vial 309,00 CHF 309.0 CHF Tempo di consegna attuale su richiesta	PKC (Protein kinase C) is a calcium-dependent and phospholipid-dependent enzyme that is activated in vivo by the lipid diacylglycero l. PKC has been shown to be involved in signal transduction and various aspects of neoplastic transformation Numero articolo: BIOV3450-100 Unità di misura: 100 MCG Imballaggio: Vial 335,00 CHF 335.0 CHF Tempo di consegna attuale su richiesta
CD40, also known as bp50 or CDW40, is a type I membrane protein found on the surface of B cells and primary carcinomas. It belongs t o the TNF-R family. CD40 serves as the receptor for CD40 ligand (CD40L Numero articolo: BIOV3178-100 Unità di misura: 100 MCG Imballaggio: Vial 373,00 CHF 373.0 CHF Tempo di consegna attuale su richiesta	PKC (Protein kinase C) is a calcium-dependent and phospholipid-dependent enzyme that is activated in vivo by the lipid diacylglycero l. PKC has been shown to be involved in signal transduction and various aspects of neoplastic transformation Numero articolo: BIOV3451-100 Unità di misura: 100 MCG Imballaggio: Vial 410,00 CHF 410.0 CHF Tempo di consegna attuale su richiesta	Human p21-GTPase-activated protein kinase 1 (PAK1) is a functional homolog of STE20 of Saccharomyces cerevisiae. PAK1 is a downstrea m effector of the Rho-family small GTPases Rac and Cdc42. A serine/threonine kinase Numero articolo: BIOV3248-100 Unità di misura: 100 MCG Imballaggio: Vial 335,00 CHF 335.0 CHF Tempo di consegna attuale su richiesta	PKGs are cyclic GMP-dependent protein kinases (also designed cGKs) that are classified into two types, PKGI and PKGII. Studies have shown that cGKs and cyclic AMP-dependent kinases (cAKs) are highly homologous protein kinase families Numero articolo: BIOV3452-100 Unità di misura: 100 MCG Imballaggio: Vial 335,00 CHF 335.0 CHF Tempo di consegna attuale su richiesta
Tau, a microtubule-binding protein which serves to stabilize microtubules in growing axons, is found to be hyperphosphorylated in pa ired helical filaments (PHF), the major fibrous component of neurofibrillary lesions associated with Alzheim Numero articolo: BIOV3453-100 Unità di misura: 100 4G Imballaggio: Vial 455,00 CHF 455.0 CHF Tempo di consegna attuale su richiesta	The matrix metalloproteinases (MMP) are a family of peptidase enzymes responsible for the degradation of extracellular matrix compon ents, including collagen, gelatin, fibronectin, laminin and proteoglycan. Numero articolo: BIOV3533-100 Unità di misura: 100 MCG Imballaggio: Vial 398,00 CHF 398.0 CHF Tempo di consegna attuale su richiesta	Chemokines play an important role in inflammation and are critical for the recruitment of effector immune cells to sites of infectio n. Chemokines activate leukocytes by binding to G protein coupled receptors. The ever-growing chemokine rece Numero articolo: BIOV3414-100 Unità di misura: 100 MCG Imballaggio: Vial 354,00 CHF 354.0 CHF Tempo di consegna attuale su richiesta	SOD (Superoxide Dismutase) is a well characterized cytosolic scavenger of oxygen free radicals that requires copper and zinc binding to potentiate its enzymatic activity. Enzymatically, SOD-1 facilitates the dismutation of oxygen radicals Numero articolo: BIOV3458-100 Unità di misura: 100 MCG Imballaggio: Vial 322,00 CHF 322.0 CHF Tempo di consegna attuale su richiesta
IkB-alpha protein is a NF-kB inhibitory protein. It binds NF-kB and retains the complex in the cytoplasm, thereby preventing it from entering into nucleus and functioning as a transcription factor. Upon receiving a variety of signals, IkB-a Numero articolo: BIOV3252-100 Unità di misura: 100 MCG Imballaggio: Vial 309,00 CHF 309.0 CHF Tempo di consegna attuale su richiesta	Serum and glucocorticoid-inducible kinase (SGK) is a serine/threonine kinase that is closely related to Akt. SGK is rapidly induced in response to a variety of stimuli, including serum, hormones, and osmotic shock, etc. Numero articolo: BIOV3459-100 Unità di misura: 100 MCG Imballaggio: Vial 309,00 CHF 309.0 CHF Tempo di consegna attuale su richiesta	ACAA2 (acetylcoenzyme A acyltransferase 2), is member of the thiolase family of enzymes and is involved in lipid metabolism. ACAA2 i s localized in the mitochondria. ACCA2 catalyzes the last conversion step of acetyl-CoA to 3-oxoacyl-CoA, in Numero articolo: BIOV3538-100 Unità di misura: 100 MCG Imballaggio: Vial 309,00 CHF 309.0 CHF Tempo di consegna attuale su richiesta	Chemokines play important roles in inflammation and critical for the recruitment of effector immune cells to sites of infection. Che mokines activate leukocytes by binding to G protein coupled receptors. Numero articolo: BIOV3419-100 Unità di misura: 100 MCG Imballaggio: Vial 309,00 CHF 309.0 CHF Tempo di consegna attuale su richiesta

VWR / Merck Prodotti chimici