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Members of the glial cell line-derived neurotropic factor (GDNF) family, including GDNF and neuturin (NTN), play key roles in the co ntrol of vertebrate neuron survival and differentiation. Physiological responses to NTN require the presence Numero articolo: BIOV6401-05 Unità di misura: 500 ML Imballaggio: Vial 284,00 CHF 284.0 CHF Tempo di consegna attuale su richiesta	Rabbit anti-mouse IgG (H+L), horseradish Peroxidase (HPR) conjμgated. This antibody has been optimized as secondary antibody in che miluminescent Western blotting applications Numero articolo: BIOV6402-05 Unità di misura: 500 ML Imballaggio: Vial 284,00 CHF 284.0 CHF Tempo di consegna attuale su richiesta	The acetylation of histone lysine residues plays a crucial role in the epigenetic regulation of gene transcription. A bromodomain is a protein domain that recognizes acetylated lysine residues such as those on the N-terminal tails of histon Numero articolo: BIOV6644-100 Unità di misura: 100 MCG Imballaggio: Vial 347,00 CHF 347.0 CHF Tempo di consegna attuale su richiesta	Synapsins are abundant brain proteins essential for regulating neurotransmitter release. All synapsins contain a short N-terminal do main that is highly conserved and phosphorylated by PKA or CaM kinase I. Phosphorylation of synapsin N-termi Numero articolo: BIOV6008-100 Unità di misura: 100 MCG Imballaggio: Vial 354,00 CHF 354.0 CHF Tempo di consegna attuale su richiesta
The sirtuins represent a distinct class of trichostatin A-insensitive lysyl-deacetylases (class III HDACs) and have been shown to ca talyze a reaction that couples lysine deacetylation to the formation of nicotinamide and O-acetyl-ADP-ribose Numero articolo: BIOV6107-50 Unità di misura: 50 MCG Imballaggio: Vial 259,00 CHF 259.0 CHF Tempo di consegna attuale su richiesta	Tudor domains are small protein structural motifs of about ~50 amino acids related to the “royal family” of methyl readers, which al so includes chromo, MBT, PWWP, and Agenet-like domains. Tudor domains occur either alone, in tandem, or Numero articolo: BIOV6109-50 Unità di misura: 50 MCG Imballaggio: Vial 284,00 CHF 284.0 CHF Tempo di consegna attuale su richiesta	Neuregulin/Heregulin is a family of structurally related polypeptide growth factors derived from alternatively spliced genes (NRG1, NRG2, NRG3 and NRG4). To date, there are over 14 soluble and transmembrane proteins derived from the NRG1 Numero articolo: BIOV6645-100 Unità di misura: 100 MCG Imballaggio: Vial 335,00 CHF 335.0 CHF Tempo di consegna attuale su richiesta	Cathepsin K, a member of the papain cysteine proteinase family is the predominant proteinase responsible for the resorption of the b one matrix. Cathepsin cleaves proteins such as collagen type I, collagen type II and osteonectin Numero articolo: BIOV6647-100 Unità di misura: 100 MCG Imballaggio: Vial 335,00 CHF 335.0 CHF Tempo di consegna attuale su richiesta
Stem cell factor / KIT ligand (SCF) is a cytokine which binds CD117(c-Kit). SCF is also known as "steel factor" or "c-kit ligand". S CF exists in two forms; cell surface bound SCF and soluble (or free) SCF. Numero articolo: BIOV6646-100 Unità di misura: 100 MCG Imballaggio: Vial 347,00 CHF 347.0 CHF Tempo di consegna attuale su richiesta	Neuregulin/Heregulin is a family of structurally related polypeptide growth factors derived from alternatively spliced genes (NRG1, NRG2, NRG3 and NRG4). To date, there are over 14 soluble and transmembrane proteins derived from the NRG1 Numero articolo: BIOV6650-100 Unità di misura: 100 MCG Imballaggio: Vial 335,00 CHF 335.0 CHF Tempo di consegna attuale su richiesta	Beta-secretase 1 (BACE1) also known as beta-site APP cleaving enzyme 1 (beta-site amyloid precursor protein cleaving enzyme 1), mema psin-2 (membrane-associated aspartic protease 2), and aspartyl protease 2 (ASP2), β-Secretase Numero articolo: BIOV6651-100 Unità di misura: 100 MCG Imballaggio: Vial 347,00 CHF 347.0 CHF Tempo di consegna attuale su richiesta	FTO (Fat mass-and obesity-associated gene) is the responsible gene for mouse ‘fused toes’ mutation. An association between FTO genot ype and type 2 diabetes has been confirmed. Numero articolo: BIOV6699-50 Unità di misura: 50 4G Imballaggio: Vial 328,00 CHF 328.0 CHF Tempo di consegna attuale su richiesta
Adenosine (ADO) is a purine nucleoside comprising a molecule of adenine attached to a ribose sugar molecule (ribofuranose) moiety v ia a β-N9-glycosidic bond. Adenosine plays an important role in biochemical processes, Numero articolo: BIOV6652-100 Unità di misura: 100 MCG Imballaggio: Vial 391,00 CHF 391.0 CHF Tempo di consegna attuale su richiesta	N6-methyladenosine (m6A), or methylation of the N6 position of adenosine is a posttranscriptional modification of RNA. Due to a lack of analytical methods, N6-methyladenosine is poorly understood, Numero articolo: BIOV6653-100 Unità di misura: 100 MCG Imballaggio: Vial 366,00 CHF 366.0 CHF Tempo di consegna attuale su richiesta	Aldehyde dehydrogenases (ALDHs) mediate the NADP+-dependent oxidation of aldehydes into acids and play an important role in the deto xification of alcohol-derived acetaldehyde, as well as in lipid peroxidation and in the metabolism of cortic Numero articolo: BIOV6750-100 Unità di misura: 100 4G Imballaggio: Vial 309,00 CHF 309.0 CHF Tempo di consegna attuale su richiesta	Guanosine is a purine nucleoside comprising of a guanine attached to a ribose (ribofuranose) ring via a β-N9-glycosidic bond. Guan osine can be phosphorylated to become guanosine monophosphate (GMP), cyclic guanosine monophosphate (cGMP), Numero articolo: BIOV6654-100 Unità di misura: 100 MCG Imballaggio: Vial 373,00 CHF 373.0 CHF Tempo di consegna attuale su richiesta
Aldehyde dehydrogenases (ALDHs) mediate the NADP+-dependent oxidation of aldehydes into acids and play an important role in the deto xification of alcohol-derived acetaldehyde, as well as in lipid peroxidation and in the metabolism of cortic Numero articolo: BIOV6751-100 Unità di misura: 100 4G Imballaggio: Vial 309,00 CHF 309.0 CHF Tempo di consegna attuale su richiesta	Cyr61 is a member of angiogenic and vasculogenic regulators designated CCN proteins, which includes CTGF, Cyr61 homolog, Fisp2. Cyr6 1 functions as an angiogenic inducer, stimulating cell adhesion and migration and promotes DNA synthesis of Numero articolo: BIOV6696-50 Unità di misura: 50 MCG Imballaggio: Vial 473,00 CHF 473.0 CHF Tempo di consegna attuale su richiesta	The TTRAP/TDP2 gene encodes a member of a superfamily of divalent cation-dependent phosphodiesterases. The encoded protein associate s with CD40, tumor necrosis factor (TNF) receptor-75 and TNF receptor associated factors (TRAFs) Numero articolo: BIOV6697-50 Unità di misura: 50 MCG Imballaggio: Vial 473,00 CHF 473.0 CHF Tempo di consegna attuale su richiesta	Tyrosyl-DNA phosphodiesterase (TDP1) is a DNA repair enzyme that catalyzes the hydrolysis of a phophodiester bond between a tyrosine residue and a DNA 3' phosphate. This protein is a member of the phospholipase D (PLD) superfamily Numero articolo: BIOV6698-50 Unità di misura: 50 MCG Imballaggio: Vial 398,00 CHF 398.0 CHF Tempo di consegna attuale su richiesta

VWR / Merck Prodotti chimici