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HTH-01-015 is a potent and selective inhibitor of NUAK1 kinase (IC₅₀ =100 nM); only weakly inhibits NUAK2 (IC₅₀ of >10 μM) and does not significantly inhibit the activity of 139 other kinases that were tested including ten AMPK family members. Numero articolo: BIOV2887-5 Unità di misura: 5 MG 209,00 CHF 209.0 CHF Aktuelle Lieferfrist auf Anfrage	PD0332991 is a highly specific inhibitor of Cdk4 (IC₅₀ = 11 nM) and Cdk6 (IC₅₀ = 16 nM). Displays selectivity for Cdk4/6 over a pane l of 34 additional protein kinases (IC₅₀ values are > 10 μM). Numero articolo: BIOV2843-5 Unità di misura: 5 MG 120,00 CHF 120.0 CHF Aktuelle Lieferfrist auf Anfrage	The tumor suppressor protein p53 is one of the key players in cancer biology. DNA damage and oxidative stress signals lead to p53 po sttranslational modifications and stabilization by binding to its consensus sequence, the p53 response element. Numero articolo: BIOVK923-100 Unità di misura: 100 AS 877,00 CHF 877.0 CHF Aktuelle Lieferfrist auf Anfrage	Dispensing Pin MINI-SPIKE® with Security Clip Numero articolo: BRAU412004 Unità di misura: 50 ST 303,00 CHF 303.0 CHF Aktuelle Lieferfrist auf Anfrage
Lyophilized Exosome Standard (30 µg, K-562 cell line) Numero articolo: BIOVM1068-6 Unità di misura: 6 VIA 1.460,00 CHF 1460.0 CHF Aktuelle Lieferfrist auf Anfrage	The Cell Stimulation Cocktail (500X) is a ready-to-use cocktail useful to induce activation of many cell types to produce cytokines. This cocktail can be used to induce cytokine production in in vitro cell culture for subsequent detection in immunoa Numero articolo: BIOVK930-SET Unità di misura: 400 4G 297,00 CHF 297.0 CHF Aktuelle Lieferfrist auf Anfrage	GSK2118436 is a selective BRAF V600E inhibitor. GSK2118436 binds to Raf family kinases and inhibits their activity. It is highly sel ective against B-Raf V600E with IC₅₀ of 0.8 nM, compared to wild type B-Raf and c-Raf with IC₅₀s of 3.2 nM and 5.0 nM Numero articolo: BIOV2800-5 Unità di misura: 5 MG 108,00 CHF 108.0 CHF Aktuelle Lieferfrist auf Anfrage	Programmed death protein 1 (PD-1) is also known as CD279 and PDCD1, is a type I membrane protein and is a member of the extended CD2 8/CTLA-4 family of T cell regulators. PDCD1 is expressed on the surface of activated T cells, B cells, macrophages, m Numero articolo: BIOVP1038-10 Unità di misura: 10 MCG 234,00 CHF 234.0 CHF Aktuelle Lieferfrist auf Anfrage
MYRISTIC ACID ALKYNE Numero articolo: CAYM13267-100 Unità di misura: 100 MCG 120,00 CHF 120.0 CHF Aktuelle Lieferfrist auf Anfrage	Sterillium Gel 100 ml hand disinfectant, UoM: 1 * 1 items Numero articolo: BODL980415_CH Unità di misura: 1 ST 6,10 CHF 6.1000000000000005 CHF Aktuelle Lieferfrist auf Anfrage	VESSEL REACTION BUBBLER 19/26 CONE Numero articolo: BIBBGB1/19 Unità di misura: 5 ST 1.170,00 CHF 1170.0 CHF Aktuelle Lieferfrist auf Anfrage	SAG hydrochloride is the water-soluble analog of SAG (Cat. No.1939). A cell-permeable Smoothened (Smo) agonist that has shown to ind uce Hedgehog pathway activation and counteract cyclopamine inhibition of Smo. Numero articolo: BIOV2801-5 Unità di misura: 5 MG 852,00 CHF 852.0 CHF Aktuelle Lieferfrist auf Anfrage
Mucin1/EMA/Episialin/CD227(VU-4H5),CF543conjugate,0.1mg/mL Numero articolo: BNC430431-500 Unità di misura: 500 4G 620,00 CHF 620.0 CHF Aktuelle Lieferfrist auf Anfrage	NT5C3B, also known 7-methylguanosine phosphate-specific 5'-nucleotidase, includes transferase activity and nucleotide binding. Among its related super-pathways are adenosine nucleotides degradation II and Pyrimidine metabolism. Numero articolo: BIOVP1040-100 Unità di misura: 100 MCG 625,00 CHF 625.0 CHF Aktuelle Lieferfrist auf Anfrage	From Streptomyces lysosuperificus. Provided as a mixture of tunicamycin A (C14), B (C15), C (C16) and D (C17) homologs in the fatty acid chain. Potent inhibitor of GlcNAc phosphotransferase which thereby inhibits glycoprotein biosynthesis. Numero articolo: BIOV2802-5 Unità di misura: 5 MG 158,00 CHF 158.0 CHF Aktuelle Lieferfrist auf Anfrage	FLASK ROUND BOTTOM 3NECK 250ML Numero articolo: BIBBFR250/4S/11P Unità di misura: 5 ST 579,00 CHF 579.0 CHF Aktuelle Lieferfrist auf Anfrage
Cerdulatinib is a novel, dual spleen tyrosine kinase (Syk) and janus kinase (JAK) inhibitor. It preferentially inhibits JAK1 and JA K3 dependent cytokine mediated signaling and functional responses in various cell types. Numero articolo: BIOV2803-25 Unità di misura: 25 MG 574,00 CHF 574.0 CHF Aktuelle Lieferfrist auf Anfrage	P7C3 is an aminopropyl carbazole derivative that acts as a proneurogenic, neuroprotective compound. Protects newborn neurons in the dentate gyrus by mitigating cell death. Also enhances learning and memory in aged rats. Orally available and brain-pe Numero articolo: BIOV2849-10 Unità di misura: 10 MG 171,00 CHF 171.0 CHF Aktuelle Lieferfrist auf Anfrage	TCS PIM-1 1 is a potent, ATP-competitive Pim-1 kinase inhibitor (IC₅₀ = 50 nM). Displays high selectivity over Pim-2 and MEK1/2 (IC₅ ₀ >20 µM). Numero articolo: BIOV2848-50 Unità di misura: 50 MG 600,00 CHF 600.0 CHF Aktuelle Lieferfrist auf Anfrage	MOXIFLOXACIN (HYDROCHLORIDE) Numero articolo: CAYM14830-1 Unità di misura: 1 G 992,00 CHF 992.0 CHF Aktuelle Lieferfrist auf Anfrage

VWR / Merck Prodotti chimici