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Ponatinib is a multi-targeted tyrosine kinase inhibitor that is active against T315I and other BCR-Abl mutants. It inhibits all tes ted BCR-Abl mutants in cellular and biochemical assays, suppresses BCR-Abl(T315I)-driven tumor growth in mice, and co Numero articolo: BIOV2712-50 Unità di misura: 50 MG 852,00 CHF 852.0 CHF Aktuelle Lieferfrist auf Anfrage	PSI-7977 is a phosphoramidate nucleotide prodrug for the treatment of hepatitis virus. It acts as a selective inhibitor of hepatitis C virus (HCV) NS5B polymerase. Numero articolo: BIOV2715-5 Unità di misura: 5 MG 221,00 CHF 221.0 CHF Aktuelle Lieferfrist auf Anfrage	Human Immunodeficiency Virus (HIV) is the cause of the Acquired Immunodeficiency Syndrome (AIDS). HIV-1 protease is a retroviral asp artyl protease (retropepsin) that is essential for the life-cycle of the virus Numero articolo: BIOVK825-100 Unità di misura: 100 AS 600,00 CHF 600.0 CHF Aktuelle Lieferfrist auf Anfrage	Translational enhancer' that drives specific mRNAs to polysomes and increases the efficiency of protein synthesis. Its association w ith the translational machinery and target mRNAs results in an increased number of initiation events per molecule of Numero articolo: BIOVP1010-100 Unità di misura: 100 MCG 864,00 CHF 864.0 CHF Aktuelle Lieferfrist auf Anfrage
Methyltransferases are a diverse group of enzymes that methylate proteins, DNA, and small molecule targets. Accordingly, methyl tran sferase activity plays a critical role in modulating gene transcription, protein interactions, and signaling networks Numero articolo: BIOVK986-100 Unità di misura: 100 AS 694,00 CHF 694.0 CHF Aktuelle Lieferfrist auf Anfrage	StemBoost™ SMAD Signaling Inhibitor Cocktail Set (1000X), Sterile- Filtered Numero articolo: BIOVK877-5ML Unità di misura: 5 ML 473,00 CHF 473.0 CHF Aktuelle Lieferfrist auf Anfrage	Senescence is thought to be a tumor suppressive mechanism and an underlying cause of aging. Senescence represents an arrested state in which the cells remain viable, but not stimulated to divide by serum or passage in culture. Numero articolo: BIOVK991-100 Unità di misura: 100 AS 776,00 CHF 776.0 CHF Aktuelle Lieferfrist auf Anfrage	DY131 is a selective agonist at estrogen-related receptors ERRβ and ERRγ. It displays minimal activity at ERRα, ERα and ERβ at conce ntrations up to 30 μM Numero articolo: BIOV2775-25 Unità di misura: 25 MG 486,00 CHF 486.0 CHF Aktuelle Lieferfrist auf Anfrage
Immunoplates for Exosome capture and quantification from human biofluids (plasma, serum, urine, saliva) and from human or mouse cell media. Transparent, white and black plates are available depending on the downstream detection approach (colorimetri Numero articolo: BIOVM1008-100-W Unità di misura: 100 AS 801,00 CHF 801.0 CHF Aktuelle Lieferfrist auf Anfrage	K252B Numero articolo: CAYM11339-1 Unità di misura: 1 MG 608,00 CHF 608.0 CHF Aktuelle Lieferfrist auf Anfrage	Ivermectin is an antiparasitic agent. It acts as a positive allosteric modulator of α7 neuronal nicotinic acetylcholine receptor; al so modulates glutamate-GABA-activated chloride channels. Numero articolo: BIOV2721-50 Unità di misura: 50 MG 82,00 CHF 82.0 CHF Aktuelle Lieferfrist auf Anfrage	Cas9 Null Protein Numero articolo: BIOVM1100-50 Unità di misura: 50 PMO 240,00 CHF 240.0 CHF Aktuelle Lieferfrist auf Anfrage
Cas9 Null Protein Numero articolo: BIOVM1100-250 Unità di misura: 250 PMO 486,00 CHF 486.0 CHF Aktuelle Lieferfrist auf Anfrage	Immunoplates for Exosome capture and quantification from human biofluids (plasma, serum, urine, saliva) and from human or mouse cell media. Transparent, white and black plates are available depending on the downstream detection approach (colorimetri Numero articolo: BIOVM1016-100-T Unità di misura: 100 AS 789,00 CHF 789.0 CHF Aktuelle Lieferfrist auf Anfrage	Cell-permeable. ML-324 is a JMJD2 histone demethylase inhibitor (JMJD2 IC₅₀ = 920 nM). Represses the expression of viral (HCMV and H SV-1) immediate early genes (IC₅₀ ~ 10 µM) and abrogates infection. Represses the reactivation of HSV from the latent Numero articolo: BIOV2763-1 Unità di misura: 1 MG 94,60 CHF 94.60000000000001 CHF Aktuelle Lieferfrist auf Anfrage	The purified total rat IgG can be used as a negative control for antibodies in Western blot, immunoprecipitation, and immunohistoche mistry, etc. Numero articolo: BIOVM1101-1000 Unità di misura: 1 MG 373,00 CHF 373.0 CHF Aktuelle Lieferfrist auf Anfrage
The purified total rat IgG can be used as a negative control for antibodies in Western blot, immunoprecipitation, and immunohistoche mistry, etc. Numero articolo: BIOVM1101-100 Unità di misura: 100 MCG 120,00 CHF 120.0 CHF Aktuelle Lieferfrist auf Anfrage	The purified total goat IgG can be used as a negative control for antibodies in Western blot, immunoprecipitation, and immunohistoch emistry, etc. Numero articolo: BIOVM1102-100 Unità di misura: 100 MCG 120,00 CHF 120.0 CHF Aktuelle Lieferfrist auf Anfrage	CONDENSER DOUBLE SURFACE 24/29 CONE Numero articolo: 201-8288 Unità di misura: 1 ST 214,00 CHF 214.0 CHF Aktuelle Lieferfrist auf Anfrage	VX-745 is a potent and selective inhibitor of p38α (IC₅₀ = 10 nM). It displays 22-fold greater selectivity versus p38β and no inhibi tion of p38γ. Also blocks TNFα production in LPS-stimulated HWB in vitro (IC₅₀ = 177 nM). Numero articolo: BIOV2812-5 Unità di misura: 5 MG 158,00 CHF 158.0 CHF Aktuelle Lieferfrist auf Anfrage

VWR / Merck Prodotti chimici