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DNA methylation, or the addition of methyl groups to cytosine bases in the dinucleotide CpG, is imperative to proper development and regulates gene expression. Item Number: BIOV3199-100 Unit of Measure: 100 MCG Packaging: Vial 347.00 CHF 347.0 CHF Current delivery time on request	Cell adhesion molecules (CAMs) are a family of closely related cell surface glycoproteins involved in cell-cell interactions during growth and are thoμght to play an important role in embryogenesis and development. BLCAM α and BLCAM β are p Item Number: BIOV3363-100 Unit of Measure: 100 MCG Packaging: Vial 322.00 CHF 322.0 CHF Current delivery time on request	Proinflammatory cytokine tumor necrosis factorα (TNF-α) contributes to a variety of inflammatory responses and programmed cell death . Item Number: BIOV3201-100 Unit of Measure: 100 MCG Packaging: Vial 335.00 CHF 335.0 CHF Current delivery time on request	Apoptosis can be induced by certain cytokines including TNF and Fas Ligand of the TNF super-family throμgh their death domain (DD) c ontaining receptors, TNFR1 and Fas. Item Number: BIOV3061R-100 Unit of Measure: 100 MCG Packaging: Vial 309.00 CHF 309.0 CHF Current delivery time on request
MAK10 protein regulates the proliferation of smooth muscle cells. The mammalian homologue of yeast MAK10, also known as EGAP, is one subunit of a novel N-terminal acetyltransferase (NAT) that is highly conserved among vertebrate species. Item Number: BIOV3134-100 Unit of Measure: 100 MCG Packaging: Vial 309.00 CHF 309.0 CHF Current delivery time on request	RIP (Receptor Interacting Protein) is a 74 kDa Ser/Thr kinase which interacts with CD95 (Fas/Apo1) receptor and the tumor necrosis f actor receptor (TNFR1). It is a cell death domain adapter protein which can bind to the adapter proteins TRA Item Number: BIOV3279-100 Unit of Measure: 100 MCG Packaging: Vial 322.00 CHF 322.0 CHF Current delivery time on request	Caspase-7 is a 34 kDa protein consisting of two subunits and a short prodomain. The procaspase-7 can be activated by cleavage by ups tream caspases to form active caspase-7 in apoptosis. Item Number: BIOV3135-100 Unit of Measure: 100 MCG Packaging: Vial 309.00 CHF 309.0 CHF Current delivery time on request	The MBD family of proteins includes MeCP2, MBD1, MBD2, MBD3 and MBD4. MBD1 (methyl-CpG binding domain protein 1) binds to methylated CpG sites and represses gene transcription. Item Number: BIOV3281-100 Unit of Measure: 100 MCG Packaging: Vial 309.00 CHF 309.0 CHF Current delivery time on request
This antibody reacts with the Stage-specific embryonic antigen-3 (SSEA-3). The epitope is expressed on the surface of human teratoca rcinoma stem cells , embryonic carcinoma (EC) cells, human embryonic germ(EG) cells and human embryonic stem Item Number: BIOV3065-25 Unit of Measure: 25 MCG Packaging: Vial 272.00 CHF 272.0 CHF Current delivery time on request	Nestin may play a role in the trafficking and distribution of IF proteins and potentially other cellular factors to daμghter cells d uring progenitor cell division (By similarity). Item Number: BIOV3208-100 Unit of Measure: 100 MCG Packaging: Vial 360.00 CHF 360.0 CHF Current delivery time on request	Cathepsin F is a cysteine protease that plays a role in invariant chain processing and major histocompatibility complex class II pep tide loading by microphages. Cathepsin F has the substrate specificity similar to that of cathepsins L and S Item Number: BIOV3371-100 Unit of Measure: 100 4G Packaging: Vial 335.00 CHF 335.0 CHF Current delivery time on request	Deoxyribonuclease I (DNase I) is a Ca2+ and Mg2+ dependent endonuclease. DNase I is synthesized in the pancreas and stored in zymoge n granules. It has been used to reduce the viscosity of cystic fibrosis sputum. Item Number: BIOV3214-100 Unit of Measure: 100 MCG Packaging: Vial 335.00 CHF 335.0 CHF Current delivery time on request
MKK3 is a protein kinase that phosphorylates the p38 MAPK. Phosphorylation by MKK3 occurs on threonine and tyrosine residues and inc reases the activity of p38 to stimulate transcription factors ATF2 and Elk-1. MKK3, together with MKK6, serv Item Number: BIOV3285-100 Unit of Measure: 100 MCG Packaging: Vial 335.00 CHF 335.0 CHF Current delivery time on request	The cathepsin family of proteolytic enzymes contains several diverse classes of proteases. The cysteine protease class comprises cat hepsins B, L, H, K, S, and O. The aspartyl protease class is composed of cathepsins D and E. Item Number: BIOV3370-200 Unit of Measure: 200 4G Packaging: Vial 360.00 CHF 360.0 CHF Current delivery time on request	Granzyme B is a 27 kDa serine protease stored in granules of activated cytotoxic T cells and NK cells. Upon target cell contact, gra nzyme B is directionally exocytosed and assisted by perforin, enters the target cell. Item Number: BIOV3073-100 Unit of Measure: 100 MCG Packaging: Vial 373.00 CHF 373.0 CHF Current delivery time on request	VENTX is a member of the Vent family of homeodomain proteins. VENTX may function as a transcriptional repressor and involved in meso dermal patterning and hemapoietic stem cell maintenance. Item Number: BIOV3286-100 Unit of Measure: 100 MCG Packaging: Vial 309.00 CHF 309.0 CHF Current delivery time on request
TACE (TNF-alpha converting enzyme, ADAM17) is a membrane-bound Metalloprotease from the ADAM (a disintegrin and Metalloprotease) fam ily of proteins. It cleaves 26kDa type II membrane-bound precursor of TNF-a into 17 kDa mature form Item Number: BIOV3222R-100 Unit of Measure: 100 MCG Packaging: Vial 335.00 CHF 335.0 CHF Current delivery time on request	Calpains are cytosolic, calcium-dependent, cysteine proteases that are ubiquitously expressed in mammalian and avian tissues. Calpai n-1 and 2 consist of a common small subunit and a large variable subunit. Item Number: BIOV3372-100 Unit of Measure: 100 4G Packaging: Vial 354.00 CHF 354.0 CHF Current delivery time on request	PARP, a 116 kDa nuclear poly (ADP-ribose) polymerase, is a highly conserved nuclear enzyme implicated in DNA repair and in the apopt osis response of cells. This protein can be cleaved by many caspases in vitro and is one of the main cleavag Item Number: BIOV3140-100 Unit of Measure: 100 MCG Packaging: Vial 486.00 CHF 486.0 CHF Current delivery time on request	PARP, a 116 kDa nuclear poly (ADP-ribose) polymerase, is a highly conserved nuclear enzyme implicated in DNA repair and in the apopt osis response of cells. This protein can be cleaved by many caspases in vitro and is one of the main cleavag Item Number: BIOV3141-100 Unit of Measure: 100 MCG Packaging: Vial 461.00 CHF 461.0 CHF Current delivery time on request

VWR / Merck Chemicals