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1-Butylpyrrolidin-2-one EMPLURA, UoM: 1 * 2,5 L, CAS: 3470-98-2 Item Number: 1.03818.2500 Unit of Measure: 2,500 L Packaging: Glass bottle 233.00 CHF 233.0 CHF Current delivery time on request	Cyclic guanosine monophosphate (cGMP) serves as a second messenger in a manner similar to that observed with cAMP. Peptide hormones, such as the natriuretic factors, activate receptors that are associated with membrane-bound guanylate cycla Item Number: BIOV3568-100 Unit of Measure: 100 4G Packaging: Vial 354.00 CHF 354.0 CHF Current delivery time on request	Tyrosine hydroxylase (TH) is the rate-limiting enzyme in the synthesis of the catecholamines dopamine and norepinephrine. TH antibod ies can therefore be used as markers for dopaminergic and noradrenergic neurons in a variety of applications Item Number: BIOV3615-100 Unit of Measure: 100 4G Packaging: Vial 448.00 CHF 448.0 CHF Current delivery time on request	Adipose tissue is an energy reserve in animals. Adipose cells produce and secrete numerous physiologically important proteins that h elp regulate whole body metabolism, such as adiponectin leptin. Item Number: BIOV3490-100 Unit of Measure: 100 MCG Packaging: Vial 335.00 CHF 335.0 CHF Current delivery time on request
Human EG-VEGF (Endocrine-gland-derived vascular endothelial growth factor) is a 9.6 kDa protein consisting of 86 amino acid residues . Human EG-VEGF induces proliferation, migration and fenestration in capillary endothelial cells derived fro Item Number: BIOV3489R-100 Unit of Measure: 100 MCG Packaging: Vial 309.00 CHF 309.0 CHF Current delivery time on request	TAB1 (TAK1 binding protein 1) is an adaptor protein that can activate TAK1 in vivo throμgh phosphorylation of TAK1, a mitogen-activa ted protein kinase kinase kinase. Once activated TAK1 phosphorylates MAPK kinase MKK4 and MKK3/6, Item Number: BIOV3682-100 Unit of Measure: 100 MCG Packaging: Vial 335.00 CHF 335.0 CHF Current delivery time on request	The nucleosome is made up of four core histone proteins (H2A, H2B, H3 and H4) and is the primary building block of chromatin. The N- terminal tail of core histones undergoes different posttranscriptional modification including acetylation Item Number: BIOV3622-100 Unit of Measure: 100 MCG Packaging: Vial 335.00 CHF 335.0 CHF Current delivery time on request	Glycogen synthase kinase 3 (GSK-3) is a serine/threonine protein kinase that has been implicated in the regulation of cell fate and in the Wnt signaling pathway. GSK-3 plays an important role in the PI3 kinase and Akt mediated cell survival Item Number: BIOV3495-100 Unit of Measure: 100 MCG Packaging: Vial 436.00 CHF 436.0 CHF Current delivery time on request
MEF2A is a member of MEF2 (myocyte enhancer factor 2) family of transcription factors. P38 phosphorylates MEF2A at Thr312 and Thr319 within the transcription activation domain and these phosphorylation events promote MEF2A –MEF2D heterodime Item Number: BIOV3683-100 Unit of Measure: 100 MCG Packaging: Vial 335.00 CHF 335.0 CHF Current delivery time on request	Wnt gene family members, including Wnt-1 throμgh Wnt-10, play a key role in regulating cellular growth and differentiation. Wnt-1 is a cysteine-rich, secreted glycoprotein that associates with cell membranes Item Number: BIOV3570-100 Unit of Measure: 100 MCG Packaging: Vial 309.00 CHF 309.0 CHF Current delivery time on request	The acetylation of histone lysine residues plays a crucial role in the epigenetic regulation of gene transcription. A bromodomain is a protein domain that recognizes acetylated lysine residues such as those on the N-terminal tails of histon Item Number: BIOV3739-100 Unit of Measure: 100 4G Packaging: Vial 335.00 CHF 335.0 CHF Current delivery time on request	Translocase of the mitochondria Outer Membrane (TOM) is essential for protein import into mitochondria. TOM40 is synthesized in the cytosol and contains information for its mitochondrial targeting and assembly. Item Number: BIOV3740-100 Unit of Measure: 100 MCG Packaging: Vial 354.00 CHF 354.0 CHF Current delivery time on request
The nucleosome is made up of four core histone proteins (H2A, H2B, H3 and H4) and is the primary building block of chromatin. The N- terminal tail of core histones undergoes different posttranscriptional modification including acetylation Item Number: BIOV3624-100 Unit of Measure: 100 MCG Packaging: Vial 335.00 CHF 335.0 CHF Current delivery time on request	HTR2C is one of the several different receptors for 5- hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotr ansmitter, a hormone, and a mitogen. This receptor mediates its action by association with G proteins Item Number: BIOV3685R-100 Unit of Measure: 100 MCG Packaging: Vial 309.00 CHF 309.0 CHF Current delivery time on request	The cysteine proteases termed lysosomal cathepsins have long been thoμght to be primarily involved in end-stage protein breakdown wi thin lysosomal compartments. Item Number: BIOV3741-100 Unit of Measure: 100 MCG Packaging: Vial 309.00 CHF 309.0 CHF Current delivery time on request	Wnt gene family members, including Wnt-1 throμgh Wnt-10, play a key role in regulating cellular growth and differentiation. Wnt-1 fu nctions as a key regulator of cellular adhesion. Item Number: BIOV3572R-100 Unit of Measure: 100 MCG Packaging: Vial 354.00 CHF 354.0 CHF Current delivery time on request
ROBO4 contains two fibronectin type-III domains and two Ig-like C2-type domains. ROBO4 is predominantly expressed in vascular endoth elium and is considered important for vascular development. ROBO4 is a receptor for Slit proteins Item Number: BIOV3625-100 Unit of Measure: 100 MCG Packaging: Vial 335.00 CHF 335.0 CHF Current delivery time on request	Lck is a membrane associated tyrosine protein kinases. The Lck gene has been shown to undergo rearrangement and overexpression in so me murine lymphomas. In human studies, it has been demonstrated that the Lck gene is localized to a site in Item Number: BIOV3498-100 Unit of Measure: 100 MCG Packaging: Vial 309.00 CHF 309.0 CHF Current delivery time on request	FOXL2 is a nuclear protein specially expressed in eyelids and in fetal and adult ovarian follicular cells. Defects in FOXL2 are caus e of blepharophimosis, ptosis and epicanthus inversus syndrome (BPES). It is an autosomal dominant disorder Item Number: BIOV3742-100 Unit of Measure: 100 MCG Packaging: Vial 309.00 CHF 309.0 CHF Current delivery time on request	Wnt gene family members, including Wnt-1 throμgh Wnt-10, play a key role in regulating cellular growth and differentiation. Wnt-1 is a cysteine-rich, secreted glycoprotein that associates with cell membranes and likely functions as a key re Item Number: BIOV3574R-100 Unit of Measure: 100 MCG Packaging: Vial 309.00 CHF 309.0 CHF Current delivery time on request

VWR / Merck Chemicals