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VWR / Merck Chemicals
IRF3 is interferon regulatory factor 3, a member of the interferon regulatory transcription factor (IRF) family. IRF3 is found in an inactive cytoplasmic form that upon serine/threonine phosphorylation forms a complex with CREBBP.
Item Number:
BIOV3877-100
Unit of Measure:
100 4G
Packaging:
Vial
347.00
CHF
347.0
CHF
Current delivery time on request
DNA binding protein 7 (DBP-7) is also known as Chd7. Mutations in the Chd7 gene is believed to be a major implication of CHARGE synd rome. CHARGE syndrome is associated with anomalies such as malformations of the heart, inner ear
Item Number:
BIOV3933-100
Unit of Measure:
100 MCG
Packaging:
Vial
309.00
CHF
309.0
CHF
Current delivery time on request
The Toll-like receptor (TLR) family of proteins are characterized by a highly conserved Toll homology (TH) domain, which is essentia l for Toll-induced signal transduction. TLRs require adapter molecule such as MyD88 and TIRAP to activate
Item Number:
BIOV3932-100
Unit of Measure:
100 MCG
Packaging:
Vial
309.00
CHF
309.0
CHF
Current delivery time on request
FKBP52 (also known as FKBP4, Hsp56, FK506 binding protein 4, p52, FKBP59) is a 55kDa peptidyl-propyl isomerase. FKBP52 catalyzes the transition between cis- and trans- proline residues which is important in immunoregulation and proper prote
Item Number:
BIOV3880-100
Unit of Measure:
100 MCG
Packaging:
Vial
309.00
CHF
309.0
CHF
Current delivery time on request
The protein encoded by this gene is a transcriptional coactivator that regulates the genes involved in energy metabolism. This prote in interacts with PPARgamma, which permits the interaction of this protein with multiple transcription facto
Item Number:
BIOV3934-100
Unit of Measure:
100 MCG
Packaging:
Vial
322.00
CHF
322.0
CHF
Current delivery time on request
MC4R (Melanocortin-4 receptor) belongs to the GPCR superfamily that is responsible for multiple signal transduction pathway which in cludes the cAMP and MAPK signaling pathways. Expression of MC4R has been reported in brain.
Item Number:
BIOV3936-100
Unit of Measure:
100 MCG
Packaging:
Vial
309.00
CHF
309.0
CHF
Current delivery time on request
Sphingosine Kinase (SphK) is a conserved lipid kinase that catalyzes the phosphorylation of sphingolipid sphingosine to sphingosine- 1-phosphate (SIP). SIP receptors coupled to cell surface G protein to regulate cell growth
Item Number:
BIOV3883-100
Unit of Measure:
100 MCG
Packaging:
Vial
309.00
CHF
309.0
CHF
Current delivery time on request
Protein arginine N-methyltransferase 5 (PRMT-5) is a member of the PRMT family that localizes to the cytoplasm in many types of tiss ues. At least three types of PRMT enzymes have been identified that shows essential regulatory functions
Item Number:
BIOV3935-100
Unit of Measure:
100 MCG
Packaging:
Vial
309.00
CHF
309.0
CHF
Current delivery time on request
Sphingosine Kinase (SphK) is a conserved lipid kinase that catalyzes the phosphorylation of sphingolipid sphingosine to sphingosine- 1-phosphate (SIP). SIP receptors coupled to cell surface G protein to regulate cell growth,
Item Number:
BIOV3884-100
Unit of Measure:
100 MCG
Packaging:
Vial
309.00
CHF
309.0
CHF
Current delivery time on request
The neurotransmitter/hormone adrenaline (epinephrine, adrenalin) plays a central role in the mammalian stress response, increasing h eart rate, raising blood pressure, and increasing blood glucose levels. Adrenaline activates both alpha-adre
Item Number:
BIOV3939-200
Unit of Measure:
200 MCG
Packaging:
Vial
354.00
CHF
354.0
CHF
Current delivery time on request
ALK7 or ACVR1C is a type I receptor for TGFB superfamily of signaling protein. Upon ligand binding, type I receptors phosphorylate c ytoplasmic SMAD transcription factors, which then translocate to the nucleus and interact directly with DNA
Item Number:
BIOV3938-100
Unit of Measure:
100 MCG
Packaging:
Vial
328.00
CHF
328.0
CHF
Current delivery time on request
Telomerase is an RNA-dependant DNA polymerase that catalyzes the addition of telemoric repeat, TTAGGG to chromosome ends. Telomerase is composed of an internal telomerase RNA template (TERC) and the enzyme, telomerase reverse transcriptase
Item Number:
BIOV3941-100
Unit of Measure:
100 MCG
Packaging:
Vial
309.00
CHF
309.0
CHF
Current delivery time on request
The adiponectin receptors, ADIPOR1 and ADIPOR2 are receptors for globular and full-length adiponectin. These receptors mediate the i ncrease of AMPK and PPAR-α ligand activities, as well as fatty acid oxidation and glucose uptake by adiponec
Item Number:
BIOV3940-200
Unit of Measure:
200 MCG
Packaging:
Vial
328.00
CHF
328.0
CHF
Current delivery time on request
Insulin stimulates glucose uptake in the muscles and adipose tissues by activating GLUT4 (Glucose Transporter Type 4). GLUT 4 is a t ransmembrane protein that facilitates glucose transport from storage sites to cell surface.
Item Number:
BIOV3945-200
Unit of Measure:
200 MCG
Packaging:
Vial
309.00
CHF
309.0
CHF
Current delivery time on request
Fibroblast Growth Factor-10 (also called KGF-2) is a heparin binding growth factor that stimulates the proliferation and activation of cells that express FGF receptors. FGF-10 is mostly related to FGF-7/KGF and is expressed during developme
Item Number:
BIOV5060R-100
Unit of Measure:
100 MCG
Packaging:
Vial
309.00
CHF
309.0
CHF
Current delivery time on request
Lipoprotein lipase (LPL) is mainly expressed in the heart, muscle and adipose tissue. LPL is a homodimer that mediates the hydrolysi s of triglycerides of very low density lipoproteins and also function as ligand/bridging factor for receptor
Item Number:
BIOV3947-100
Unit of Measure:
100 MCG
Packaging:
Vial
341.00
CHF
341.0
CHF
Current delivery time on request
The FGFs plays an important role in regulating tissue growth, morphogenesis and tissue repair. FGF-18 is a newly discovered heparin binding growth factor that stimulates the proliferation and activation of cells that express FGF receptors.
Item Number:
BIOV5082-100
Unit of Measure:
100 MCG
Packaging:
Vial
309.00
CHF
309.0
CHF
Current delivery time on request
Damage-regulated autophagy modulator (DRAM) is a p53 target gene encoding a lysosomal protein that induces autophagy, a process that degrades cytosolic proteins and organelles.
Item Number:
BIOV5075-100
Unit of Measure:
100 MCG
Packaging:
Vial
410.00
CHF
410.0
CHF
Current delivery time on request
Fractalkine, also known as neurotactin, is a membrane-bound CX3C Chemokine. The mature protein is part of a 397-amino acid precursor and consists of a chemokine domain of 76 amino acids, a mucin stalk of 241 amino acids
Item Number:
BIOV5088-100
Unit of Measure:
100 MCG
Packaging:
Vial
309.00
CHF
309.0
CHF
Current delivery time on request
Granulocyte Colony Stimulating Factor (G-CSF) is a potent stimulator of bone marrow cells, especially those of neutrophil lineage. I n addition, G-CSF can enhance the survival and activate the immunological functions of mature neutrophils.
Item Number:
BIOV5094-100
Unit of Measure:
100 MCG
Packaging:
Vial
309.00
CHF
309.0
CHF
Current delivery time on request
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