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Accumulation of the amyloid-beta (Abeta) plaque in the cerebral cortex is a critical event in the pathogenesis of Alzheimer's diseas e. Abeta peptide is generated by proteolytic cleavage of the beta-amyloid protein precursor (APP) Numero articolo: BIOV5051-100 Unità di misura: 100 MCG Imballaggio: Vial 410,00 CHF 410.0 CHF Tempo di consegna attuale su richiesta	Fibroblast Growth Factor-8 (FGF-8) is also known as Androgen-induced Growth Factor (AIGF), a heparin binding growth factor, which st imulates the proliferation and activation of cells that express the FGF receptors. Recombinant human FGF-8 i Numero articolo: BIOV5053-100 Unità di misura: 100 MCG Imballaggio: Vial 309,00 CHF 309.0 CHF Tempo di consegna attuale su richiesta	Interleukin-12 is a disulfide-linked heterodimeric protein (p70), composed of two subunits, p35 and p40, which are encoded by two di fferent genes. Recombinant Human IL-12 p40 produced in E.Coli is a single, non-glycosylated polypeptide Numero articolo: BIOV5732-100 Unità di misura: 100 MCG Imballaggio: Vial 309,00 CHF 309.0 CHF Tempo di consegna attuale su richiesta	Produced from sera of rabbits pre-immunized with highly pure (>98%) recombinant rat IL-6. The antibody was purified by affinity chro matography employing immobilized rat IL-6 matrix. Numero articolo: BIOV5145-100 Unità di misura: 100 MCG Imballaggio: Vial 335,00 CHF 335.0 CHF Tempo di consegna attuale su richiesta
BMPs (bone morphogenetic proteins) belong to the TGF-β superfamily of structurally related signaling proteins. As implied by their n ame, BMPs promote and regulate bone development, growth, remodeling and repair, in both prenatal development Numero articolo: BIOV5572-100 Unità di misura: 100 MCG Imballaggio: Vial 309,00 CHF 309.0 CHF Tempo di consegna attuale su richiesta	Fibroblast Growth Factor-10 (also called KGF-2) is a heparin binding growth factor that stimulates the proliferation and activation of cells that express FGF receptors. FGF-10 is mostly related to FGF-7/KGF and is expressed during developme Numero articolo: BIOV5060A-100 Unità di misura: 100 MCG Imballaggio: Vial 309,00 CHF 309.0 CHF Tempo di consegna attuale su richiesta	IL-7 is a hematopoietic growth factor which affects primarily early B and T cells. Produced by thymic stromal cells, spleen cells an d keratinocytes, IL-7 can also co-stimulate the proliferation of mature T cells in combination with other Numero articolo: BIOV5148-100 Unità di misura: 100 MCG Imballaggio: Vial 309,00 CHF 309.0 CHF Tempo di consegna attuale su richiesta	PlGF-1(also called Placenta Growth Factor-1, PLGF, and PGF) is an angiogenic factor that belongs to the cysteine-knot superfamily of growth factors. PlGF-1 is expressed in placental tissues, colon and mammary carcinomas. Numero articolo: BIOV5739-100 Unità di misura: 100 MCG Imballaggio: Vial 335,00 CHF 335.0 CHF Tempo di consegna attuale su richiesta
Human 4-1BB Ligand (4-1BBL) is a member of the emerging family of Ligands with structural homology to tumor necrosis factor. Human 4 -1BBL is a 19.5 kDa protein containing 185 amino acid residues, comprising the TNF-like extra-cellular domai Numero articolo: BIOV5369-100 Unità di misura: 100 MCG Imballaggio: Vial 309,00 CHF 309.0 CHF Tempo di consegna attuale su richiesta	IL-8 is a proinflammatory CXC chemokine that can signal throμgh the CXCR1 and CXCR2 receptors. It is secreted by monocytes and endot helial cells. IL-8 chemoattracts and activates neutrophils. Numero articolo: BIOV5149-100 Unità di misura: 100 MCG Imballaggio: Vial 335,00 CHF 335.0 CHF Tempo di consegna attuale su richiesta	PLGF (also called Placenta Growth Factor, PIGF, PGF) is an angiogenic factor that belongs to the cysteine-knot superfamily of growth factors. PLGF is expressed in placental tissues, colon and mammary carcinomas. It signals throμgh the VEGFR Numero articolo: BIOV5743-100 Unità di misura: 100 MCG Imballaggio: Vial 335,00 CHF 335.0 CHF Tempo di consegna attuale su richiesta	Produced from sera of rabbits pre-immunized with highly pure (>98%) recombinant human IL-13. The antibody was purified by affinity c hromatography employing immobilized human IL-13 matrix. Numero articolo: BIOV5164-100 Unità di misura: 100 MCG Imballaggio: Vial 335,00 CHF 335.0 CHF Tempo di consegna attuale su richiesta
Interleukin-13 (IL-13) is an immunoregulatory protein produced by activated T lymphocytes. The biological activities of IL-13 includ e the stimulation of B cell proliferation and immunoglobulins production. Numero articolo: BIOV5165-100 Unità di misura: 100 MCG Imballaggio: Vial 335,00 CHF 335.0 CHF Tempo di consegna attuale su richiesta	The phosphorylation of histone H3 plays an important role in gene expression, chromatin remodeling, chromosome condensation, and cel l division. Histone H3 phosphorylation may initiate at different phases of the cell division Numero articolo: BIOV6119-50 Unità di misura: 50 MCG Imballaggio: Vial 309,00 CHF 309.0 CHF Tempo di consegna attuale su richiesta	PAI-1 (plasminogen activator inhibitor-1) is originally cloned from human endothelial cell and rat hepatoma cell cDNA libraries. As a member of the serpin family of serine protease inhibitors, PAI-1 inhibits both tissue-type palsminogen act Numero articolo: BIOV5579-100 Unità di misura: 100 MCG Imballaggio: Vial 335,00 CHF 335.0 CHF Tempo di consegna attuale su richiesta	Wnt-1 is a secreted protein that signals throμgh the Frizzled family of cell surface receptors and is required for normal embryonic development. Wnt-1 activation induces a complex signaling cascade that ultimately leads to the increased exp Numero articolo: BIOV5754-100 Unità di misura: 100 MCG Imballaggio: Vial 309,00 CHF 309.0 CHF Tempo di consegna attuale su richiesta
EZH1 is a human homolog of the Drosophila gene Enhancer of zeste E(z), a member of the polycomb group of transcriptional repressors. In mice, EZH1 is a regulator of homeotic gene expression Numero articolo: BIOV6123-50 Unità di misura: 50 MCG Imballaggio: Vial 259,00 CHF 259.0 CHF Tempo di consegna attuale su richiesta	Lymphotactin is the only C chemokine so far identified which has a single cysteine residue near the amino terminus. It has 114 amino acids with a 22 amino acids signal peptide. It is produced in activated CD8+ T cells and NK cells. Numero articolo: BIOV5377-100 Unità di misura: 100 MCG Imballaggio: Vial 335,00 CHF 335.0 CHF Tempo di consegna attuale su richiesta	BMPs (bone morphogenetic proteins) belong to the TGF-β superfamily of structurally related signaling proteins. As implied by their n ame, BMPs promote and regulate bone development, growth, remodeling and repair, in both prenatal development Numero articolo: BIOV5580-100 Unità di misura: 100 MCG Imballaggio: Vial 309,00 CHF 309.0 CHF Tempo di consegna attuale su richiesta	The Trefoil Factor peptides (TFF1, TFF2 and TFF3) are expressed in the gastrointestinal tract, and appear to play an important role in intestinal mucosal defense and repair. TFF2 has been shown to inhibit gastrointestinal motility Numero articolo: BIOV5745-100 Unità di misura: 100 MCG Imballaggio: Vial 309,00 CHF 309.0 CHF Tempo di consegna attuale su richiesta

VWR / Merck Prodotti chimici