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Wee1 is a nuclear tyrosine protein kinase. The protein plays a role in suppressing eukaryotes’ entry into mitosis by inactivating cd c2 kinase by inhibiting tyrosine phosphorylation. The predicted molecular weight of the kinase is 72 kDa. Numero articolo: BIOV3120-100 Unità di misura: 100 MCG Imballaggio: Vial 335,00 CHF 335.0 CHF Tempo di consegna attuale su richiesta	c-Jun is a component of the transcription factor AP-1 that binds and activates transcription at TRE/AP-1 elements. Numero articolo: BIOV3009-100 Unità di misura: 100 MCG Imballaggio: Vial 309,00 CHF 309.0 CHF Tempo di consegna attuale su richiesta	NIK (NF-kB-inducing kinase) is a member of the MAP kinase kinase kinase family that binds TRAF2 and stimulates NF-kB activity. NIK w as initially isolated from a human B cell cDNA library and contains 795 amino acids with an apparent molecul Numero articolo: BIOV3193R-100 Unità di misura: 100 MCG Imballaggio: Vial 322,00 CHF 322.0 CHF Tempo di consegna attuale su richiesta	FATP4 is a transmembrane protein that is involved in the uptake and metabolism of long chain fatty acids. FATP4 has acyl-CoA synth ase activity and contains an AMP-binding motif. FATP4 is linked to insulin resistance and metabolic disorde Numero articolo: BIOV3268-100 Unità di misura: 100 MCG Imballaggio: Vial 309,00 CHF 309.0 CHF Tempo di consegna attuale su richiesta
SATURATED/MONOUNSATURATED FATTY ACID LC/ Numero articolo: CAYM17942-1 Unità di misura: 1 ST Imballaggio: Amber ampule 114,00 CHF 114.0 CHF Tempo di consegna attuale su richiesta	The transcription factor ATF-2 (also called CRE-BP1) is a member of the ATF/CREB family of leucine zipper proteins. ATF-2 forms homo dimers and heterodimers with c-Jun to initiate CRE-dependent transcription. Phosphorylation of ATF-2 at Thr6 Numero articolo: BIOV3359-100 Unità di misura: 100 MCG Imballaggio: Vial 410,00 CHF 410.0 CHF Tempo di consegna attuale su richiesta	Bad is a member of the Bcl-2 family protein that selectively dimerize with Bcl-xL and Bcl-2 resulting in cell death. Survival factor s such as IL-3 can inhibit the apoptotic activity of Bad by activating intracellular signaling pathways that Numero articolo: BIOV3269-100 Unità di misura: 100 MCG Imballaggio: Vial 410,00 CHF 410.0 CHF Tempo di consegna attuale su richiesta	Transcription factor CREB binds the cAMP response element (CRE) and activates transcription in response to a variety of extracellula r signals including neurotransmitters, hormones, membrane depolarization, and growth or neurotrophic factors Numero articolo: BIOV3360R-100 Unità di misura: 100 MCG Imballaggio: Vial 309,00 CHF 309.0 CHF Tempo di consegna attuale su richiesta
Histone-lysine N- methyltransferase SETD3 has a function as methylation of Lys36 of histone H3 which represents a specific tag for e pigenetic transcriptional activation. It is highly expressed in muscular tissues. Numero articolo: BIOV3197-200 Unità di misura: 200 MCG Imballaggio: Vial 347,00 CHF 347.0 CHF Tempo di consegna attuale su richiesta	$Bid, a BH3 domain-containing proapoptotic Bcl-2 family member, is localized in the cytosolic fraction of cells as an inactive precur sor. Its active form is generated upon proteolytic cleavage by caspase-8 in the Fas signaling pathway.$ Bid, a BH3 domain-containing proapoptotic Bcl-2 family member, is localized in the cytosolic fraction of cells as an inactive precur sor. Its active form is generated upon proteolytic cleavage by caspase-8 in the Fas signaling pathway. Numero articolo: BIOV3272-100 Unità di misura: 100 MCG Imballaggio: Vial 309,00 CHF 309.0 CHF Tempo di consegna attuale su richiesta	COX proteins are membrane-associated heme proteins that have cyclooxygenase and peroxidase activities. These enzymes are targets of NSAID (Nonsteroidal anti-inflammatory drμgs) such as aspirin. Prostaglandins (PGs) formed by the enzymatic a Numero articolo: BIOV3361-100 Unità di misura: 100 MCG Imballaggio: Vial 309,00 CHF 309.0 CHF Tempo di consegna attuale su richiesta	c-FLIP was cloned by several labs independently and termed Casper, I-FLICE, FLAME-1, CASH AND CLARP. c-FLIP contains two death effec tor domains and has sequence homology to caspase-8. c-FLIP interacts Numero articolo: BIOV3058-100 Unità di misura: 100 MCG Imballaggio: Vial 309,00 CHF 309.0 CHF Tempo di consegna attuale su richiesta
Hexokinases phosphorylate glucose to produce glucose-6-phosphate, thus committing glucose to the glycolytic pathway. This gene encod es hexokinase 3. Similar to hexokinases 1 and 2, this allosteric enzyme is inhibited by its product glucose- Numero articolo: BIOV3198-100 Unità di misura: 100 MCG Imballaggio: Vial 360,00 CHF 360.0 CHF Tempo di consegna attuale su richiesta	Tumor Necrosis Factor-alpha (TNF-α) is a potent lymphoid factor that exerts cytotoxic effects on a wide range of tumor cells and cer tain other target cells. Rat TNF-α is a 17 kDa protein containing 157 amino acid residues. Numero articolo: BIOV3054-100 Unità di misura: 100 MCG Imballaggio: Vial 309,00 CHF 309.0 CHF Tempo di consegna attuale su richiesta	Lamins are nuclear membrane structural components that are important in maintaining normal cell functions such as cell cycle control , DNA replication and chromatin organization. Numero articolo: BIOV3267-100 Unità di misura: 100 MCG Imballaggio: Vial 309,00 CHF 309.0 CHF Tempo di consegna attuale su richiesta	Arginine methylation is an important protein modification catalyzed by arginine methyltransferase such as PRMT7. PRMT7 has two methy ltransferase domains each containing a putative AdoMet binding motif. Numero articolo: BIOV3059-100 Unità di misura: 100 MCG Imballaggio: Vial 309,00 CHF 309.0 CHF Tempo di consegna attuale su richiesta
DNA methylation, or the addition of methyl groups to cytosine bases in the dinucleotide CpG, is imperative to proper development and regulates gene expression. Numero articolo: BIOV3199-100 Unità di misura: 100 MCG Imballaggio: Vial 347,00 CHF 347.0 CHF Tempo di consegna attuale su richiesta	Methylation of DNA at cytosine residues plays an important role in regulation of gene expression, genomic imprinting, and is essenti al for mammalian development. Hypermethylation of CpG islands in tumor suppressor genes or hypomethylation o Numero articolo: BIOV3275-100 Unità di misura: 100 MCG Imballaggio: Vial 347,00 CHF 347.0 CHF Tempo di consegna attuale su richiesta	Cell adhesion molecules (CAMs) are a family of closely related cell surface glycoproteins involved in cell-cell interactions during growth and are thoμght to play an important role in embryogenesis and development. BLCAM α and BLCAM β are p Numero articolo: BIOV3363-100 Unità di misura: 100 MCG Imballaggio: Vial 322,00 CHF 322.0 CHF Tempo di consegna attuale su richiesta	Proinflammatory cytokine tumor necrosis factorα (TNF-α) contributes to a variety of inflammatory responses and programmed cell death . Numero articolo: BIOV3201-100 Unità di misura: 100 MCG Imballaggio: Vial 335,00 CHF 335.0 CHF Tempo di consegna attuale su richiesta

VWR / Merck Prodotti chimici