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FOXP3 a member of the forkhead/winge-helix family of transcriptional regulators and is highly conserved in humans. It has been propo sed that FOXP3 may be a master regulatory gene and marker for Treg cells. Recent reports also sμggest expres Numero articolo: BIOV3709-100 Unità di misura: 100 MCG Imballaggio: Vial 309,00 CHF 309.0 CHF Tempo di consegna attuale su richiesta	The mammalian target of rapamycin (mTOR, FRAP, RAFT) is a Ser/Thr protein kinase that functions as an ATP and amino acid sensor to b alance nutrient availability and cell growth. Numero articolo: BIOV3786-100 Unità di misura: 100 4G Imballaggio: Vial 436,00 CHF 436.0 CHF Tempo di consegna attuale su richiesta	EGF-like module-containing mucin-like receptor 2 (EMR2) is a member of the class B seven-span transmembrane (TM7) receptor family. E MR2 is expressed predominantly by cells of the immune system such as leukocytes. Numero articolo: BIOV3652-100 Unità di misura: 100 MCG Imballaggio: Vial 309,00 CHF 309.0 CHF Tempo di consegna attuale su richiesta	PLC (Phosphoinositide-specific phospholipase C) plays a significant role in transmembrane signaling. Four members of PLCs have been identified: PLCβ, PLCg, PLCd, and PLCe. In response to extracellular stimuli (e.g., hormone, growth factors, Numero articolo: BIOV3710-100 Unità di misura: 100 MCG Imballaggio: Vial 309,00 CHF 309.0 CHF Tempo di consegna attuale su richiesta
Sox genes encode for transcriptional regulators that are involved in the early embryonic develpoment and in the determination of cel l fate. Sox2 is also known as SRY (sex determining region Y)-box2, contain genes that encode for the HMG-box Numero articolo: BIOV3889-100 Unità di misura: 100 MCG Imballaggio: Vial 309,00 CHF 309.0 CHF Tempo di consegna attuale su richiesta	Rho-associated protein kinase 2 (ROCK2), or Rho kinase alpha, is a serine-threonine protein kinase that plays an important role in c ellular apoptosis, growth, cell motility and cell contraction. ROCK2 shares an overall 65% homology in amino Numero articolo: BIOV3789-100 Unità di misura: 100 4G Imballaggio: Vial 436,00 CHF 436.0 CHF Tempo di consegna attuale su richiesta	Zinc finger and BTB domain-containing protein 7A (LRF, Pokemon, FBI1) is a transcriptional repressor encoded by the ZBTB7A gene that belongs to the POK (POZ and Kruppel)/ZBTB (zinc finger and BTB) family. LRF is broadly expressed with eleva Numero articolo: BIOV3791-100 Unità di misura: 100 4G Imballaggio: Vial 436,00 CHF 436.0 CHF Tempo di consegna attuale su richiesta	Endothelial lipase (EL) is a member of the triglyceride lipase gene family. It functions primarily as a phospholipase and has low tr iglyceride lipase activity. It was originally cloned from endothelial cells Numero articolo: BIOV3657-100 Unità di misura: 100 MCG Imballaggio: Vial 354,00 CHF 354.0 CHF Tempo di consegna attuale su richiesta
OX40 is also known as CD134 is a member of the tumor necrosis factor receptor superfamily (TNFR). OX40 plays an important role in CD 4+ and CD8+T-cells and B-cells response. Binding of OX40 to its ligand, OX40L provides co-stimulatory signa Numero articolo: BIOV3890-100 Unità di misura: 100 MCG Imballaggio: Vial 309,00 CHF 309.0 CHF Tempo di consegna attuale su richiesta	Cathepsin V, also known as Cathepsin L2 and Cathepsin U, is a cysteine protease of the papain family. It is expressed as a proenzyme in lysosomes, which can be autocatalytically converted to the mature form at pH 4.0. Cathepsin V is specifi Numero articolo: BIOV3712-100 Unità di misura: 100 MCG Imballaggio: Vial 309,00 CHF 309.0 CHF Tempo di consegna attuale su richiesta	Galectin-9 is an eosinophile chemoattractant produced by activated T lymphocytes. It is an integral membrane protein that plays a ro le in immuno/inflammation processes that causes inflammatory reactions in the central nervous system (CNS). Numero articolo: BIOV3827-100 Unità di misura: 100 MCG Imballaggio: Vial 309,00 CHF 309.0 CHF Tempo di consegna attuale su richiesta	PRMT1 methylate’s (mono & asymmetric dimethylation) the guanidino nitrogens of arginyl residues present in a glycine and arginine-ri ch domain (may methylate HNRNPA1 and histones) methylate’s SUPT5H. The PRMT1 protein functions as a histone Numero articolo: BIOV3792-100 Unità di misura: 100 4G Imballaggio: Vial 436,00 CHF 436.0 CHF Tempo di consegna attuale su richiesta
Retinoblastoma binding protein 5 (RbBP5) is a subunit of a human Set1-like histone methyltransferase (HMT) complex. The Set-1 like c omplexes are responsible for mono-, di-, and tri-methylation of histone H3 K4. RbBP5 associates with a multi Numero articolo: BIOV3793-100 Unità di misura: 100 4G Imballaggio: Vial 436,00 CHF 436.0 CHF Tempo di consegna attuale su richiesta	Math1 belongs to the basic helix-loop-helix (BHLH) family of transcription factors. It activates E-box dependent transcription along with E47. It is neural-specific and is switched on during differentiation into neuroectoderm. Numero articolo: BIOV3658-100 Unità di misura: 100 MCG Imballaggio: Vial 354,00 CHF 354.0 CHF Tempo di consegna attuale su richiesta	LDL-related proteins LRP-5 and LRP-6. are members of the LDL receptor superfamily, which were found to be involved in the canonical Wnt signaling pathway. Mammalian LRP-6 was shown to bind to Wnt-1 and enhance Induced-induced developmental Numero articolo: BIOV3714-100 Unità di misura: 100 MCG Imballaggio: Vial 328,00 CHF 328.0 CHF Tempo di consegna attuale su richiesta	FMOC-LYS(BOC)-NOVASYN TGA Numero articolo: NOVA8.56032.0025 Unità di misura: 25 G Imballaggio: Glass bottle 2.380,00 CHF 2380.0 CHF Tempo di consegna attuale su richiesta
Retinoblastoma binding protein 5 (RbBP5) belongs to a highly conserved subfamily of WD-repeat proteins and it is also a subunit of a human Set1-like histone methyltransferase (HMT) complex. The encoded RbBP 5protein interacts preferentially Numero articolo: BIOV3793R-100 Unità di misura: 100 MCG Imballaggio: Vial 309,00 CHF 309.0 CHF Tempo di consegna attuale su richiesta	DNA methylation can help regulate transcriptional silencing via repressive transcription complexes, which include methyl-CpG-binding domain protein and Histone deacetylases (HDACs) DNMT1. This core enzyme for mammalian DNA methylation can a Numero articolo: BIOV3715-100 Unità di misura: 100 MCG Imballaggio: Vial 309,00 CHF 309.0 CHF Tempo di consegna attuale su richiesta	FoxH1 (also known as Forkhead box H1 or FAST-1) is a transcription factor that shares close homology with Xenopus FAST-1. FoxH1 bind s to SMAD2/4 and activates activin response throμgh a DNA binding motif region that consist of TGT(G/T)(T/G) Numero articolo: BIOV3892-100 Unità di misura: 100 MCG Imballaggio: Vial 309,00 CHF 309.0 CHF Tempo di consegna attuale su richiesta	CtBP1 is a cellular phosphoprotein that associates with various proteins and functions as a corepressor of transcription. CtBP1 and the related protein CtBP2 are characterized as C-terminal binding protein of adenovirus E1A Numero articolo: BIOV3796-100 Unità di misura: 100 4G Imballaggio: Vial 436,00 CHF 436.0 CHF Tempo di consegna attuale su richiesta

VWR / Merck Prodotti chimici